N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide

N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide Basic information
Product Name:N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide
Synonyms:N,N'-BIS(2,3-DIHYDROXYPROPYL)-2,4,6-TRIIODO-5-NITRO-1,3-BENZENEDICARBOXAMIDE;N,N`-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenediformamide;N,N-Bis-(2,3-dihydroxypropyl)-5-nitroisophthalamide;5-AMINO C N,N'' C BIS (2,3-DIHYDROXYPROPYL)-2,4,6-TRIIODO-1,3-BENZENEDICARBOXAMIDE;N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide;5-Nitro-N,NBis(2,3-Dihydroxypropyl)-1,3-Benzenedicarbolamide;Iohexol Related Compound C (50 mg) (N,N'-bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide);5-Nitro-N,N'-bis(2,3-dihydroxypropyl)isophthalamide
CAS:76820-34-3
MF:C14H19N3O8
MW:357.32
EINECS:616-392-7
Product Categories:Aromatics;Intermediates;Labeling and Diagnostics Reagents
Mol File:76820-34-3.mol
N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide Structure
N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide Chemical Properties
Melting point >140°C (dec.)
density 1.347 at 20℃
storage temp. 2-8°C
solubility DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
form Solid
color White to Off-White
Stability:Hygroscopic
LogP-1.36 at 23℃ and pH6
CAS DataBase Reference76820-34-3(CAS DataBase Reference)
Safety Information
HS Code 2924296000
MSDS Information
N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide Usage And Synthesis
DescriptionN,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide is a non-ionic organic compound that can be used as a reaction intermediate for the preparation of amidated iodinated x-ray contrast media. The amidation reaction is typically carried out in aqueous solution with an acid catalyst at room temperature for up to 24 hours. The amidation reaction condition and time can be optimized depending on the desired end product. Industrial preparation of iohexol typically involves the use of an x-ray generator and iopamidol, which is synthesized from diethylene triamine and ethylenediamine.
Chemical PropertiesWhite to Off-White Solid.
UsesN,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide is used in the preparation of X-ray contrast agents.
N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide Preparation Products And Raw materials
4-IODO-3-NITROTOLUENE PHTHALAMIDE 5-Amino-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide 4-iodo-3-nitrobenzamide POLY(N-ISOPROPYL ACRYLAMIDE) N-Isopropylacrylamide Iohexol NITROGEN DIOXIDE IOHEXOL RELATED COMPOUND C (100 MG) (N,N'-BIS(2,3-DIHYDROXYPROPYL)-5-NITRO-1,3-BENZENEDICARBOXAMIDE) N,N-Dimethylformamide 2-IODO-5-NITROTOLUENE N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide 5-Amino-N,N'-bis(2,3-dihydroxypropyl)isophthalamide Lauramidopropyl betaine 2-Iodo-1-methyl-3-nitro-benzene Azodicarbonamide 1-Iodo-4-nitrobenzene Cocoyl amide propyldimethyl glycine

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