12-Hydroxy Irinotecan

12-Hydroxy Irinotecan Basic information
Product Name:12-Hydroxy Irinotecan
Synonyms:12-Hydroxy Irinotecan;(4S)-4,11-Diethyl-4,12-dihydroxy-9-[(4-piperidinopiperidino)carbonyloxy]-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione;[1,4'-Bipiperidine]-1'-carboxylic Acid (4S)-4,11-diethyl-3,4,12,14-tetrahydro- 4,12-dihydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl Ester;Irinotecan 12-Hydroxy IMpurity;RPR 112524;12-Hydroxy Irinotecan (Mixture of Diastereomers);Irinotecan EP Impurity M DiHCl;Irinotecan Impurity M
CAS:185336-12-3
MF:C33H38N4O7
MW:602.68
EINECS:
Product Categories:Aromatics, Chiral Reagents, Heterocycles, Inhibitors, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals;Aromatics;Chiral Reagents;Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals
Mol File:185336-12-3.mol
12-Hydroxy Irinotecan Structure
12-Hydroxy Irinotecan Chemical Properties
Melting point >221°C (dec.)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), Dichloromethane (Slightly), DMSO (Slightly)
form Solid
color White to Light Orange
Stability:Hygroscopic
Safety Information
MSDS Information
12-Hydroxy Irinotecan Usage And Synthesis
UsesA metabolite of Irinotecan (I767500) found in human bile and urine.
12-Hydroxy Irinotecan Preparation Products And Raw materials
sodium:(2S)-2-[12-ethyl-8-(hydroxymethyl)-9-oxo-2-(4-piperidin-1-ylpiperidine-1-carbonyl)oxy-11H-indolizino[1,2-b]quinolin-7-yl]-2-hydroxybutanoate 7,11-Diethyl-10-hydroxycaMptothecin Irinotecan Impurity 6 Irinotecan EP Impurity H 1-CHLOROCARBONYL-4-PIPERIDINOPIPERIDINE 10-Hydroxycamptothecin 7-Ethyl-10-hydroxycamptothecin 1-Piperidinecarbonyl chloride, 4-oxo- (9CI) Irinotecan hydrochloride trihydrate Irinotecan IMpurity G 1,4'-Bipiperidine, 1'-(phenylmethyl)- 12-ethyl-8-methyl-9-oxo-7-propionyl-9,11-dihydroindolizino[1,2-b]quinolin-2-yl [1,4'-bipiperidine]-1'-carboxylate Irinotecan Impurity 3 Irinotecan Impurity 26 4-Piperidinone 11-Desethyl Irinotecan Irinotecan Impurity 19 Irinotecan Hydroxyl Acid

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