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Fmoc-D-leucine

Fmoc-D-leucine Basic information
Product Name:Fmoc-D-leucine
Synonyms:FMOC-D-BETA-LEU-OH;FMOC-D-LEU-OH;FMOC-D-LEUCINE;FMOC-D-LEU;9-FLUORENYLMETHOXYCARBONYL-D-LEUCINE;FMOC-D-LEU-OH 99+%;n-[(9h-fluoren-9-ylmethoxy)carbonyl]-d-leucine;n-fmoc-d-leucine
CAS:114360-54-2
MF:C21H23NO4
MW:353.41
EINECS:252-662-7
Product Categories:Leucine [Leu, L];Fmoc-Amino Acids and Derivatives;Amino Acids (N-Protected);Biochemistry;Fmoc-Amino Acids;Fmoc-Amino acid series;Fluorenes, Flurenones;Amino Acids
Mol File:114360-54-2.mol
Fmoc-D-leucine Structure
Fmoc-D-leucine Chemical Properties
Melting point 155°C
Boiling point 559.8±33.0 °C(Predicted)
density 1?+-.0.06 g/cm3(Predicted)
refractive index 25 ° (C=1, DMF)
storage temp. 2-8°C
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka3.91±0.21(Predicted)
form powder to crystal
color White to Almost white
Water Solubility Insoluble in water.
CAS DataBase Reference114360-54-2(CAS DataBase Reference)
Safety Information
Safety Statements 22-24/25
WGK Germany 3
F 10
HS Code 29224999
MSDS Information
ProviderLanguage
SigmaAldrich English
Fmoc-D-leucine Usage And Synthesis
Chemical PropertiesWhite powder
UsesA convergent synthesis of the proposed structure of (+)-pestalazine B has been achieved in 4 steps using the N-alkylation of an unprotected tryptophan diketopiperazine with a 3a-bromopyrrolidinoindoline where the condensation between L-tryptophan methyl ester and N-Fmoc-D-leucine in the presence of EDC as coupling agent afforded the corresponding L-Trp-D-Leu dipeptide.
DefinitionChEBI: Fmoc-D-Leu-OH is a leucine derivative.
Fmoc-D-leucine Preparation Products And Raw materials
FMOC-T-BUTYL-D-ALANINE FMOC-D-GLA(OTBU)2-OH N-alpha-FMOC-Nepsilon-BOC-L-Lysine Fmoc-Asp(OtBu)-OH FMOC-D-CHA-OH Fmoc-D-leucine Nalpha-Fmoc-Ndelta-trityl-L-glutamine Fmoc-Leu-OH L-Fmoc-Aspartic acid alpha-tert-butyl ester D-2-Amino-4-methylpentanoic acid 9-Fluorenylmethyl chloroformate FMOC-TOAC-OH Fmoc-Phe-OH L-Leucine Fmoc N-(9-Fluorenylmethoxycarbonyloxy)succinimide N-CARBOBENZOXY-DL-LEUCINE L-tert-Leucine
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