ChemicalBook Product Catalog Surfactant Non-ionic surfactants Polyol ester type Span 20

Span 20

Span 20 Basic information
Product Name:Span 20
Synonyms:EmulsifierS20;radiasurf7125;Arlasel 20;emsorb2515;emulsifier(s20);Span 20 CAS NO.1338-39-2;Sorbitan Monolaurate (Span-20);Span #20 (Sorbitan monolaurate)
CAS:1338-39-2
MF:C18H34O6
MW:346.46
EINECS:215-663-3
Product Categories:Cosmetic Ingredients & Chemicals;Ester Type (Surfactants);Functional Materials;Nonionic Surfactants;Surfactants
Mol File:1338-39-2.mol
Span 20 Structure
Span 20 Chemical Properties
Boiling point 401.18°C (rough estimate)
density 1.032 g/mL at 25 °C(lit.)
vapor pressure <1.3 hPa (20 °C)
refractive index n20/D 1.474(lit.)
Fp >230 °F
storage temp. Store below +30°C.
solubility Practically insoluble, but dispersible in water, miscible with alcohol.
form Liquid
color Clear amber colour
Specific Gravity1.032
Water Solubility Soluble in 2-ethoxyethanol, ethanol and methanol. Not miscible or difficult to mix in water.
Merck 14,8724
Hydrophilic-Lipophilic Balance (HLB)8.6
LogP3.366 (est)
CAS DataBase Reference1338-39-2(CAS DataBase Reference)
EPA Substance Registry SystemSorbitan monolaurate (1338-39-2)
Safety Information
Safety Statements 24/25
WGK Germany 1
RTECS WG2920000
F 10-23
TSCA Yes
HS Code 34021300
ToxicityLD50 orally in Rabbit: 33600 mg/kg
MSDS Information
ProviderLanguage
Sorbitan laurate English
SigmaAldrich English
ALFA English
Span 20 Usage And Synthesis
Chemical PropertiesBrownish-yellow, viscous liquid.
UsesLonzest(R) SML is used as a lubricant and as an emulsifier.
Usessorbitan laurate is an emulsifier in cosmetic creams and lotions as well as a stabilizer of essential oils in water.
UsesSorbitan Monolaurate is a detergent and monoester of lauric acid and hexitol anhydrides derived from sorbitol.
UsesSpan 20 has been used in a study to assess enhanced solubility and oral bioavailability of itraconazole. It has also been used in a study to investigate the oxidation of unsaturated lipids in oil-in-water emulsions.
Brand nameSpan 20 (ICI Americas).
General DescriptionSpan 20 is a co-surfactant.
Safety ProfileSlightly toxic by ingestion. Questionable carcinogen with experimental neoplastigenic data. When heated to decomposition it emits acrid smoke and irritating fumes.
Span 20 Preparation Products And Raw materials
Raw materialsLauric acid-->Sorbitol-->Span 60
Span 80 Sorbitan monopalmitate SORBITAN TRISTEARATE Span 60 Sorbitan, dioctadecanoate Food emulgent Isosorbide Bitumen emulsifier Span 20 Metalaxyl Sorbitan Sucrose Fatty Acid Ester Sorbitan, octadecanoate (2:3) Triton X-100 Phthalates Sorbitol EMULSIFIER Propylamine
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