1H-Imidazol-5-amine,1-methyl-4-nitro-(9CI)

1H-Imidazol-5-amine,1-methyl-4-nitro-(9CI) Basic information
Product Name:1H-Imidazol-5-amine,1-methyl-4-nitro-(9CI)
Synonyms:1H-Imidazol-5-amine,1-methyl-4-nitro-(9CI);(3-methyl-5-nitro-imidazol-4-yl)amine;3-methyl-5-nitro-imidazol-4-amine;3-methyl-5-nitroimidazol-4-amine;Azathioprine impurity A;1-Methyl-4-nitro-1H-imidazol-5-amine;5-Amino-1-methyl-4-nitroimidazole;Azathioprine EP Impurity A
CAS:4531-54-8
MF:C4H6N4O2
MW:142.12
EINECS:
Product Categories:NITRO
Mol File:4531-54-8.mol
1H-Imidazol-5-amine,1-methyl-4-nitro-(9CI) Structure
1H-Imidazol-5-amine,1-methyl-4-nitro-(9CI) Chemical Properties
Melting point >288°C (dec.)
Boiling point 435.0±25.0 °C(Predicted)
density 1.67±0.1 g/cm3(Predicted)
storage temp. Hygroscopic, Refrigerator, under inert atmosphere
solubility DMSO (Slightly, Heated), Methanol (Very Slightly, Heated)
pka1.07±0.61(Predicted)
form neat
color Light Yellow to Light Green
Safety Information
HS Code 2933997500
MSDS Information
1H-Imidazol-5-amine,1-methyl-4-nitro-(9CI) Usage And Synthesis
Uses5-Amino-1-methyl-4-nitroimidazole is a moiety of Azathioprine (A803350); an immunosuppressive antimetabolite that is also active as a disease modifying antirheumatic drug (DMARD).
1H-Imidazol-5-amine,1-methyl-4-nitro-(9CI) Preparation Products And Raw materials
Raw materials1-methyl-4,5-dinitro-imidazole-->Imidazole, 1-methyl-4-nitro--->5-Chloro-1-methyl-4-nitroimidazole-->Cyclohexanone-->Morpholine
6,6DITHIOBISPURINE Epalrestat iMpurity GUANERAN Ethanone, 1-[6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-9H-purin-9-yl]- 8-Methyl-7H-purin-6-ol 9H-Purine, 9-β-D-arabinofuranosyl-6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]- 4,5-Dichloroimidazole Ezetimibe Impurity Azathioprine IMpurity E Azathioprine impurity F 1,7-DIHYDRO-2-METHYL-6-PURINONE 6-Hydroxypurine Azathioprine EP Impurity E 5-mercapto-1-methyl-4-nitroimidazole Azathioprine impurity B Azathioprine Azathioprine Impurity 1 Azathioprine-13C2-15N

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