|
| | Gadobutrol Basic information |
| Product Name: | Gadobutrol | | Synonyms: | Gadobutrol;GadoliniuM,[10-[2,3-dihydroxy-1-(hydroxyMethyl)propyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triacetato(3-)-kN1,kN4,kN7,kN10,kO1,kO4,kO7]-;gallium 10-(1,3,4-trihydroxybutan-2-yl)-1,4,7,10-tetraazacyclododecane-1,4,7-tricarboxylate;CL124;gadolinium(III) 2,2',2''-(10-((2R,3S)-1,3,4-trihydroxybutan-2-yl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetate;CS-113;gudobutrol;Ggadobutrol | | CAS: | 138071-82-6 | | MF: | C18H31N4O9.Gd | | MW: | 604.712 | | EINECS: | 1308068-626-2 | | Product Categories: | API | | Mol File: | 138071-82-6.mol |  |
| | Gadobutrol Chemical Properties |
| Melting point | >264°C (dec.) | | density | 1.3 g/mL at 37 °C | | storage temp. | Refrigerator | | solubility | Water (Slightly) | | form | Solid | | color | White to Off-White | | PH | 6.6-8 |
| Toxicity | LD50 i.v. in mice: 23 mmol/kg (Vogler) |
| | Gadobutrol Usage And Synthesis |
| Uses | Gadobutrol is a gadolinium-based MRI contrast agent (GBCA). | | Uses | Gadobutrol injection is a magnetic resonance imaging (MRI) contrast agent that is used to help create a clear picture of the body during an MRI scan. MRI scans are a special kind of procedure that lets a doctor look at the inside of the body, such as the brain. | | Mechanism of action | In the central nervous system, Gadobutrol works by highlighting any areas with disrupted blood brain barrier (BBB) and/or abnormal vascularity. In breast tissue, Gadobutrol exposes the presence and extent of malignant breast disease. | | Waste Disposal | Expired or waste pharmaceuticals shall carefully take into consideration
applicable DEA, EPA, and FDA regulations. It is not appropriate to
dispose by flushing the pharmaceutical down the toilet or discarding to
trash. If possible return the pharmaceutical to the manufacturer for
proper disposal being careful to properly label and securely package the
material. Alternatively, the waste pharmaceutical shall be labeled,
securely packaged and transported by a state licensed medical waste
contractor to dispose by burial in a licensed hazardous or toxic waste
landfill or incinerator. |
| | Gadobutrol Preparation Products And Raw materials |
|
