7-(ALPHA-BROMOACETAMIDO)CEPHALOSPORANIC ACID

7-(ALPHA-BROMOACETAMIDO)CEPHALOSPORANIC ACID Basic information
Product Name:7-(ALPHA-BROMOACETAMIDO)CEPHALOSPORANIC ACID
Synonyms:7-(2-Bromoacetamido)cephalosporanic Acid(7-Bromoacetylaminocephalosporanic Acid);Cefathiamidine Impurity C: (6R-trans)-3-[(Acetyloxy)methyl]-7-[(bromoacetyl)amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid;(6R,7R)-3-(acetyloxymethyl)-7-[(2-bromoacetyl)amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;7-(ALPHA-BROMOACETAMIDO)CEPHALOSPORANIC ACID;7-(a-Bromoacetamido)cephalosporanicacid;3[(Acetyloxy)methyl]-7-[(bromoacetyl)amino]-8-oxo-(6R-trans)-5-thia-1-azabicyclo[4,2,0]oct-2-ene-2-carboxylicacid;(6R-trans)-3-[(Acetyloxy)Methyl]-7-[(broMoacetyl)aMino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid;7-(2-BroMoacetaMido)cephalosporanic Acid
CAS:26973-80-8
MF:C12H13BrN2O6S
MW:393.21
EINECS:
Product Categories:Amines;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;MTS & Sulfhydryl Active Reagents;Pharmaceuticals
Mol File:26973-80-8.mol
7-(ALPHA-BROMOACETAMIDO)CEPHALOSPORANIC ACID Structure
7-(ALPHA-BROMOACETAMIDO)CEPHALOSPORANIC ACID Chemical Properties
Boiling point 711.2±60.0 °C(Predicted)
density 1.81±0.1 g/cm3(Predicted)
storage temp. Amber Vial, Refrigerator, Under inert atmosphere
solubility Chloroform, Dichloromethane, Dimethyl Sulfoxide
form Solid
pka2.67±0.50(Predicted)
color Off-white
Safety Information
MSDS Information
7-(ALPHA-BROMOACETAMIDO)CEPHALOSPORANIC ACID Usage And Synthesis
Chemical PropertiesOff-white Solid
UsesAn analog of glutaryl-7-amino cephalosporanic acid (GL-7-ACA). Can inhibit and specifically alkylate GL-7-ACA acylase (C130) from Pseudomonas sp.130 by forming a carbon-carbon bond between BA-7-ACA and the C-2 on indole ring of Trp-β4 residue of C130.
7-(ALPHA-BROMOACETAMIDO)CEPHALOSPORANIC ACID Preparation Products And Raw materials
Preparation ProductsCEFATHIAMIDINE
Cefathiamidine Impurity 3 Desacetyl CefathiaMidine Cefathiamidine Impurity 10 CefathiaMidine Lactone Cefmetazole Impurity 4 Cefmetazole Lactone 4',5'-dihydrocefradine Cefathiamidine Impurity 11 CEFATHIAMIDINE 7-[[[(CyanoMethyl)thio]acetyl]aMino]-7-Methoxy Cephalosporanic Acid Cefathiamidine Impurity 5 7-(ALPHA-BROMOACETAMIDO)CEPHALOSPORANIC ACID 7-Aminocephalosporanic acid

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