3,4-Dimethoxyphenylacetone

3,4-Dimethoxyphenylacetone Basic information
Product Name:3,4-Dimethoxyphenylacetone
Synonyms:Veratone;Veratrum ketone;3,4-DIMETHOXYPHENYLACETONE / METHYL VERATRYL KETONE;3,4-DIMETHOXYPHENYLACETONE 97+%;VERATRYL ACETONE;1-(3,4-dimethoxyphenyl)acetone;1-(3,4-DIMETHOXYPHENYL)-2-PROPANONE;1-ACETONYL-3,4-DIMETHOXYBENZENE
CAS:776-99-8
MF:C11H14O3
MW:194.23
EINECS:212-285-0
Product Categories:Aromatic Ketones (substituted);C11 to C12;Carbonyl Compounds;Ketones;Building Blocks;C11 to C12;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks;776-99-8
Mol File:776-99-8.mol
3,4-Dimethoxyphenylacetone Structure
3,4-Dimethoxyphenylacetone Chemical Properties
Melting point 136-139 °C
Boiling point 154-158 °C (12 mmHg)
density 1.115 g/mL at 25 °C(lit.)
refractive index n20/D 1.5358(lit.)
Fp >230 °F
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Sparingly), Methanol (Slightly)
form clear liquid
color Light yellow to Yellow to Orange
Water Solubility Insoluble in water.
BRN 1107410
CAS DataBase Reference776-99-8(CAS DataBase Reference)
NIST Chemistry Reference3,4-Dimethoxyphenylacetone(776-99-8)
Safety Information
Risk Statements 36/37/38
Safety Statements 24/25
WGK Germany 3
RTECS UC1795500
HS Code 29145090
MSDS Information
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3,4-Dimethoxyphenylacetone Usage And Synthesis
Chemical PropertiesCLEAR YELLOW TO BROWN LIQUID
Uses3,4-Dimethoxyphenylacetone was used as starting material in the synthesis of α-methyl-dopa, an important nonproteogenic α-amino acid for pharmaceutical applications. 3,4-Dimethoxyphenylacetone undergoes asymmetric amination catalyzed by Brevibacterium linens IFO 12141 strain to yield corresponding optically active amine
Synthesis Reference(s)Chemistry Letters, 5, p. 1239, 1976
The Journal of Organic Chemistry, 29, p. 1424, 1964 DOI: 10.1021/jo01029a039
3-AMINO-2-(3,4-DIMETHOXYPHENYL)INDEN-1-ONE 2-(3,4-DIMETHOXYPHENYL)-3-((3-NITROPHENYL)AMINO)INDEN-1-ONE ALLOCRYPTOPINE 2-(3,4-DIMETHOXYPHENYL)-3-((4-FLUOROPHENYL)AMINO)INDEN-1-ONE 6,7-Dimethoxy-2-tetralone POMIFERIN-3',4'-DIMETHYL ETHER 2-(3,4-DIMETHOXYPHENYL)-3-((4-METHYLPHENYL)AMINO)INDEN-1-ONE 2-CHLORO-3' 4'-DIMETHOXYBENZIL 97 1,1-Dimethoxyethane ISOPOMIFERIN-3',4'-DIMETHYL ETHER 2,5-DIMETHOXYPHENYLACETONE 2-(3,4-DIMETHOXYPHENYL)-3-((4-CHLOROPHENYL)AMINO)INDEN-1-ONE 2-(3,4-DIMETHOXYPHENYL)-3-((4-ISOPROPYLPHENYL)AMINO)INDEN-1-ONE 4H-1-Benzopyran-4-one, 3-(3,4-dimethoxyphenyl)-7-methoxy- 3',4'-DIMETHOXY-7-HYDROXYISOFLAVONE 2-(3,4-DIMETHOXYPHENYL)-3-((4-(3-(TRIFLUOROMETHYL)PHENOXY)PHENYL)AMINO)INDEN-1-ONE 2-(3,4-DIMETHOXYPHENYL)-3-((4-IODOPHENYL)AMINO)INDEN-1-ONE 3'-methoxypropiophenone

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