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2'-Deoxycytidine-5'-monophosphoric acid

2'-Deoxycytidine-5'-monophosphoric acid Basic information
Product Name:2'-Deoxycytidine-5'-monophosphoric acid
Synonyms:2''-DEOXYCYTIDINE-5''-MONOPHOSPHATE (WRITE CRYSTALLINE POWDER 98-100%);5''-CYTIDYLIC ACID, 2''-DEOXY-;2''-DEOXYCYTIDINE 5''-MONOPHOSPHATE FREE ACID (DCMP);2'-Deoxycytidine 5'-Monophosphate Hydrate;dCMP, Deoxycytidylic acid;2'-Deoxycytidine-5'-monpohosphate free acid;dCMP.H2;(2R)-4-(Phosphonomethyl)piperazine-2-carboxylic acid
CAS:1032-65-1
MF:C9H14N3O7P
MW:307.2
EINECS:213-849-9
Product Categories:Nucleic acids;Bases & Related Reagents;Pyridines, Pyrimidines, Purines and Pteredines;Biochemistry;Nucleosides, Nucleotides & Related Reagents;Nucleotides and their analogs;Carbohydrates & Derivatives;Heterocycles;Nucleotides;Phosphorylating and Phosphitylating Agents
Mol File:1032-65-1.mol
2'-Deoxycytidine-5'-monophosphoric acid Structure
2'-Deoxycytidine-5'-monophosphoric acid Chemical Properties
Melting point 169-172 °C (dec.)
Boiling point 633.8±65.0 °C(Predicted)
density 2.01±0.1 g/cm3(Predicted)
refractive index 37 ° (C=1, H2O)
storage temp. -20°C
solubility H2O: 10 mg/mL, clear, colorless
pka1.86±0.10(Predicted)
form Crystalline Powder
color White
Water Solubility Soluble in water.
BRN 41062
CAS DataBase Reference1032-65-1(CAS DataBase Reference)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 20/21/22-36/37/38
Safety Statements 22-24/25-37/39-36-26
WGK Germany 3
F 10-21
HS Code 29349990
MSDS Information
ProviderLanguage
2'-Deoxycytidine-5'-monophosphoric acid English
SigmaAldrich English
2'-Deoxycytidine-5'-monophosphoric acid Usage And Synthesis
Chemical PropertiesCrystalline
UsesA phosphorylated metabolite of the deoxyribonucleoside 2’Deoxycytidine. A constituent of Deoxyribonucleic acid. Studies show that it increases influenza virus antigen-induced immune cell proliferatio n.
Uses2'-Deoxycytidine-5'-monophosphate is used as a substrate of uridine monophosphate (UMP)/cytidine monophosphate (CMP) kinase (EC 2.7.4.4) to form dCDP which upon phosphorylation to dCTP supports DNA and RNA biosynthesis.
DefinitionChEBI: Dianion of 2'-deoxycytidine 5'-monophosphate arising from deprotonation of both OH groups of the phosphate.
General Description2′-Deoxycytidine 5′-monophosphate is a deoxynucleotide building block via which DNA is made. It consists of a 2′-deoxy-β-D-ribofuranose, linked through an N-β-D-glycosidic linkage to a heterocycle nitrogen cytosine. It is phosphorylated at carbon C-5′.
Purification MethodsRecrystallise the acid from H2O or aqueous EtOH and dry it in a vacuum. [Volkin et al. J Am Chem Soc 73 1533 1951, UV: Fox et al. J Am Chem Soc 75 4315 1953, IR: Michelson & Todd J Chem Soc 3438 1954, Beilstein 25 IV 3664.]
2'-Deoxycytidine-5'-monophosphoric acid Preparation Products And Raw materials
Raw materials2'-Deoxycytidine monohydrate
Preparation Products2-AMino-9-[5-(hydroxyMethyl)oxolan-2-yl]-3H-purin-6-one
Cytidine-5'-triphosphate disodium salt dihydrate Hyaluronic acid Citicoline sodium DCTP NA Ethyl 2-(Chlorosulfonyl)acetate 2'-Deoxycytidine-5'-monophosphoric acid Ascoric Acid 2'-Deoxycytidine-5'-diphosphate trisodium salt Cytidine 5′-(tetrahydrogen triphosphate), xsodium salt, hydrate 5-Azacytidine Stearic acid Folic acid APC Cytarabine CDP MOPSO CYTIDYLYL-(3'->5')-CYTIDINE Citric acid
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