Difurazone

Difurazone Basic information
Product Name:Difurazone
Synonyms:NITROVIN;((3-(5-nitro-2-furyl)-1-(2-(5-nitro-2-furyl)vinyl)allylidene)amino)guanidine;1,5-bis(5-nitro-2-furanyl)-1,4-pentadien-3-one,(aminoiminomethyl)hydrazone;1,5-bis(5-nitro-2-furyl)-3-pentadienoneamidinonhydrazone;1,5-bis(5-nitro-2-furyl)-3-pentadienoneguanylhydrazone;1-(3-(5-nitro-2-furyl)-1-(2-(5-nitro-2-furyl)vinyl)allylideneamino)guanidine hydrochloride;1,5-di(5-nitro-2-furyl)pentadien-3-one amidinohydrazone hydrochloride;bis(5-nitrofurfurylidene)acetoneguanylhydrazone
CAS:804-36-4
MF:C14H12N6O6
MW:360.28
EINECS:212-358-7
Product Categories:
Mol File:804-36-4.mol
Difurazone Structure
Difurazone Chemical Properties
Melting point 217° (dec)
Boiling point 492.33°C (rough estimate)
density 1.3634 (rough estimate)
refractive index 1.6800 (estimate)
storage temp. 2-8°C
pka7.72±0.70(Predicted)
color Blackish-violet crystals from EtOH
CAS DataBase Reference804-36-4(CAS DataBase Reference)
IARC3 (Vol. 31, Sup 7) 1987
Safety Information
Safety Statements 24/25
HS Code 29411099
Toxicitymmo-sat 2500 ng/L CEHYAN 32,276,87
MSDS Information
Difurazone Usage And Synthesis
DefinitionChEBI: Nitrovin is a member of furans and a C-nitro compound.
Brand namePanzon;Payzone.
World Health Organization (WHO)Difurazone, a nitrofuran derivative, was formerly used as an antiinfective agent. It has, however, been superseded by safer compounds and WHO has no information to suggest that it remains commercially available.
Safety ProfilePoison by intraperitoneal route. Moderately toxic by subcutaneous route. Mildly toxic by ingestion. Questionable carcinogen. A growth promoter in chickens. Mutation data reported. When heated to decomposition it emits very toxic fumes of NOx.
Difurazone Preparation Products And Raw materials
Raw materials5-Nitrofurfural-->AMINOGUANIDINE
Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate 2-NITROFURAN 4-Nitrobenzonitrile Nitrovin hydrochloride Difurazone Diacetone acrylamide 2-Butanone Glycine Methylene dithiocyanate Guanidine hydrochloride 1,4-PENTADIENE N,N'-Methylenebisacrylamide 1-Deuteriopropan-2-one Pentachlorophenol Diacetone Alcohol

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