TYRPHOSTIN AG 1290

TYRPHOSTIN AG 1290 Basic information
Product Name:TYRPHOSTIN AG 1290
Synonyms:TYRPHOSTIN AG 1290;Entacapone acid;(E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)prop-2-enoic acid;Entacapone Impurity 6(Entacapone EP Impurity F);XDDDOLQEZBJWFZ-LZCJLJQNSA-N;Entacapone impurity F;Entacapone Impurity 22(Entacapone EP Impurity F);(2E)-2-Cyano-3-(3,4-dihydroxy-5-nit
CAS:160391-70-8
MF:C10H6N2O6
MW:250.16
EINECS:
Product Categories:
Mol File:160391-70-8.mol
TYRPHOSTIN AG 1290 Structure
TYRPHOSTIN AG 1290 Chemical Properties
Boiling point 478.9±45.0 °C(Predicted)
density 1.744±0.06 g/cm3(Predicted)
form Yellow to green solid.
pka0.51±0.10(Predicted)
Safety Information
MSDS Information
TYRPHOSTIN AG 1290 Usage And Synthesis
UsesEntacapone Acid, is the acid derivative of Entacapone (E558500). (E)-Isomer of Entacapone polymorphic form A. Peripherally acting inhibitor of catechol-O-methyl transferase (COMT), an enzyme involved in the metabolism of catecholamine neurotransmitters and related drugs. Antiparkinsonian.
TYRPHOSTIN AG 1290 Preparation Products And Raw materials
3,4-Dihydroxy-5-Nitrobenzoic Acid (E/Z)-3-O-Methyl Entacapone Entacapone EP IMpurity B (alphaE)-alpha-[(3,4-Dihydroxy-5-nitrophenyl)methylene]-beta-oxo-1-piperidinepropanenitrile Entacapone 4-β-D-Glucuronide 2-Propenamide, 2-cyano-3-(3,4-dihydroxyphenyl)-N,N-diethyl-, (2E)- Entacapone Impurity 13 Entacapone 3-b-D-Glucuronide Entacapone EP Impurity G 3,5-DINITROCATECHOL 6-Methoxy-2,4-dinitrophenol Entacapone EP IMpurity D (E)-3-O-Methyl Entacapone CIS-ENTACAPONE 3-Nitro-4,5-dihydroxybenzaldehyde Entacapone EP IMpurity I Entacapone Impurity 4 Entacapone Impurity 10

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