4-MORPHOLIN-4-YL-1,2,5-THIADIAZOL-3-OL

4-MORPHOLIN-4-YL-1,2,5-THIADIAZOL-3-OL Basic information
Product Name:4-MORPHOLIN-4-YL-1,2,5-THIADIAZOL-3-OL
Synonyms:Timolol EP Impurity D Timolol EP Impurity D;Timolol Maleate EP Impurity D;4-MORPHOLIN-4-YL-1,2,5-THIADIAZOL-3-OL;4-Morpholin-4-yl-1,2,5-thiadiazol-3-ol 97%;3-Hydroxy-4-morpholino-1,2,5-thiazole;4-morpholino-1,2,5-thiadiazol-3-ol;3-Hydroxy-4-(morpholin-4-yl)-1,2,5-thiadiazole 97%;3-Hydroxy-4-(morpholin-4-yl)-1,2,5-thiadiazole
CAS:30165-97-0
MF:C6H9N3O2S
MW:187.22
EINECS:608-450-5
Product Categories:Heterocycles;Sulfur & Selenium Compounds;Oxadiazoles & Thiadiazoles;Oxadiazoles & Thiadiazoles
Mol File:30165-97-0.mol
4-MORPHOLIN-4-YL-1,2,5-THIADIAZOL-3-OL Structure
4-MORPHOLIN-4-YL-1,2,5-THIADIAZOL-3-OL Chemical Properties
Melting point 200-204 °C
density 1.69±0.1 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly, Heated and Sonicated)
form Solid
pka6.20±0.40(Predicted)
color White to Off-White
Safety Information
HS Code 2934990002
MSDS Information
4-MORPHOLIN-4-YL-1,2,5-THIADIAZOL-3-OL Usage And Synthesis
Chemical PropertiesOff-White Solid
Uses3-Hydroxy-4-morpholino-1,2,5-thiazole (Timolol EP Impurity D; Timolol BP Impurity D; Timolol USP Related Compound D) is an intermediate for the preparation of Timolol.
4-MORPHOLIN-4-YL-1,2,5-THIADIAZOL-3-OL Preparation Products And Raw materials
Raw materialsTimolol-->3-Chloro-4-morpholino-1,2,5-thiadiazole
Preparation Products(+)-1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol
Morpholinazole TiMolol IMpurity E Timolol Timolol EP Impurity G D-Timolol maleate (4-MORPHOLIN-4-YL-[1,2,5]THIADIAZOL-3-YLOXY)-ACETIC ACID 4-MORPHOLIN-4-YL-1,2,5-THIADIAZOL-3-OL Timolol (S)-Timolol maleate ETHYL 2-[(4-MORPHOLINO-1,2,5-THIADIAZOL-3-YL)OXY]ACETATE 4-MORPHOLIN-4-YL-1,2,5-THIADIAZOL-3-YL CHLOROACETATE AURORA KA-7120 1,2,5-THIADIAZOL-3-OL

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