|
| | 3-Bromo-9H-carbazole Basic information |
| | 3-Bromo-9H-carbazole Chemical Properties |
| Melting point | 195 °C | | Boiling point | 160℃/6mm | | density | 1.617±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | pka | 16.43±0.30(Predicted) | | form | Solid | | color | White | | Water Solubility | Slightly soluble in water. | | InChIKey | LTBWKAYPXIIVPC-UHFFFAOYSA-N | | EPA Substance Registry System | 3-Bromocarbazole (1592-95-6) |
| | 3-Bromo-9H-carbazole Usage And Synthesis |
| Chemical Properties | White to light yellow solid | | Uses | 3-Bromocarbazole is used as a intermediate for organic light-emitting diode(OLED) and pharmaceutical. | | Uses | 3-Bromo-9H-carbazole is an aryl hydrocarbon receptor agonist. A standard for environmental testing and research. Substance for the bological potency study, characterization of mono to tetra-halogenated carbazoles. | | Preparation | 3-Bromocarbazole synthesis: A solution of N-bromosuccinimide (1.1g, 5.98mmol) in dimethylformamide was added dropwise to a solution of carbazole (1, 1g, 5.96mmol) in dimethylformamide (15mL) at 0°C. The reaction mixture was then stirred at room temperature for 24h. The reaction was poured into distilled water to give a cream coloured precipitate. The precipitate was filtered off under vacuum and washed with distilled water (3 × 20mL). The precipitate was dissolved in ethyl acetate, dried with sodium sulfate and filtered. Upon concentration under reduced pressure the crude product was obtained as a brown solid. After crystallisation of the crude product with chloroform, the pure 3-Bromo-9H-carbazole(692 mg, 47%) was obtained as white crystals. Rf (ethyl acetate/hexane, 1:6 v/v): 0.43; melting point: 200–201°C. |
| | 3-Bromo-9H-carbazole Preparation Products And Raw materials |
| Raw materials | Benzene, 1-broMo-4-nitroso--->CHEMBRDG-BB 5356400-->3-Bromo-9-phenylcarbazole-->3,6-Dibromocarbazole-->6-bromo-2,3,4,9-tetrahydro-1H-carbazole-->4-broMo-2-iodo-1-nitrobenzene-->4-bromo-2-phenyl aniline-->4-Bromophenylhydrazine hydrochloride-->2-(TRIMETHYLSILYL)PHENYL TRIFLUOROMETHANESULFONATE | | Preparation Products | 3-BroMo-9-(4-broMophenyl)carbazole-->9-Phenyl-9H,9'H-[3,3']bicarbazolyl-->9H-Carbazole, 3-(4-dibenzothienyl)--->3,3'-Bicarbazole-->9-[1,1'-Biphenyl-4-yl]-3-bromo-9H-carbazole |
|
