DL-4-HYDROXYPHENYLGLYCINE

DL-4-HYDROXYPHENYLGLYCINE Basic information
Product Name:DL-4-HYDROXYPHENYLGLYCINE
Synonyms:DL-4-OH-Phg-OH;4-HYDROXY-DL-PHENYLGLYCINE;2-Amino-2-(4-hydroxyphenyl)aceticacid;(4-Hydroxyphenyl)(amino)acetic acid;2-(4-Hydroxyphenyl)glycine;2-amino-2-(4-hydroxyphenyl)acetic acid (en);4-[Amino(carboxy)methyl]phenol;4-[Amino(carboxy)methyl]phenol, Amino(4-hydroxyphenyl)acetic acid
CAS:938-97-6
MF:C8H9NO3
MW:167.16
EINECS:213-353-2
Product Categories:pharmacetical;Pharmaceutical Intermediates;bc0001
Mol File:938-97-6.mol
DL-4-HYDROXYPHENYLGLYCINE Structure
DL-4-HYDROXYPHENYLGLYCINE Chemical Properties
Melting point 229-230 °C
Boiling point 365.8±32.0 °C(Predicted)
density 1.396±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility DMSO (Very Slightly, Heated), Water (Slightly, Heated, Sonicated)
form Solid
pka2.15±0.10(Predicted)
color White to Pale Yellow
CAS DataBase Reference938-97-6(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
HazardClass IRRITANT
HS Code 2918290090
MSDS Information
DL-4-HYDROXYPHENYLGLYCINE Usage And Synthesis
Uses4-hydroxyphenylglycine is used (now only rarely) as a photographic developer and in the determination of phosphorus and silicon.
Uses(4-Hydroxyphenyl)glycine, is a key intermediate for the synthesis Cefpiramide (C243400), used as a β-lactam antibiotic.
DefinitionChEBI: 4-hydroxyphenylglycine is a glycine molecule carrying a 4-hydroxyphenyl substituent. It has a role as a bacterial metabolite. It is functionally related to a glycine.
Synthesis Reference(s)Journal of the American Chemical Society, 93, p. 2897, 1971 DOI: 10.1021/ja00741a013
DL-4-HYDROXYPHENYLGLYCINE Preparation Products And Raw materials
Raw materialsHydrogen bromide-->Sodium cyanide-->Ammonium bicarbonate-->p-Anisaldehyde-->4-Aminophenylacetic acid-->5-(4-METHOXYPHENYL)HYDATOIN
RARECHEM AL BO 1224 Potassium (R)-((3-ethoxy-1-methyl-3-oxoprop-1-enyl)amino)(4-hydroxyphenyl)acetate DL-P-Hydroxyphenylglycine 2-amino-2-(4-ethoxyphenyl)propanoic acid DL-4-HYDROXYPHENYLGLYCINE D-(-)-A-4-HYDROXYPHENYLGLYCINE DANE SALT METHYL POTASSIUM D-(3,4-DIHYDROXY) A-PHENYLGLYCINE AMINO-(3,4,5-TRIMETHOXY-PHENYL)-ACETIC ACID (RS)-3-CARBOXY-4-HYDROXYPHENYLGLYCINE (RS)-ALPHA-METHYL-3-CARBOXY-4-HYDROXYPHENYLGLYCINE (2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl)acetic acid AMINO-(4-ETHOXY-PHENYL)-ACETIC ACID (S)-3-CARBOXY-4-HYDROXYPHENYLGLYCINE AMINO-(3,4-DIHYDROXY-PHENYL)-ACETIC ACID (R)-3-CARBOXY-4-HYDROXYPHENYLGLYCINE 2-amino-2-(4-propoxyphenyl)propanoic acid 2-AMINO-2-(4-METHOXYPHENYL)ACETIC ACID L-TYROSINE, [U-14C]

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