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| | (S)-TERT-BUTYL 1-(CHLOROMETHYL)-5-HYDROXY-1H-BENZO[E]INDOLE-3(2H)-CARBOXYLATE Basic information |
| Product Name: | (S)-TERT-BUTYL 1-(CHLOROMETHYL)-5-HYDROXY-1H-BENZO[E]INDOLE-3(2H)-CARBOXYLATE | | Synonyms: | (S)-TERT-BUTYL 1-(CHLOROMETHYL)-5-HYDROXY-1H-BENZO[E]INDOLE-3(2H)-CARBOXYLATE;tert-Butyl (S)-1-(chloromethyl)-5-hydroxy-1,2-dihydro-3H-benzo[e]indole-3-carboxylate;N-Boc-seco-CBI;3H-Benz[e]indole-3-carboxylic acid, 1-(chloromethyl)-1,2-dihydro-5-hydroxy-, 1,1-dimethylethyl ester, (1S)-;(S)-tert-Butyl 1-(chloromethyl)-5-hydroxy-1H-benzo[e]indole-3(2H)-carboxylate 95% (HPLC) | | CAS: | 130007-86-2 | | MF: | C18H20ClNO3 | | MW: | 333.81 | | EINECS: | | | Product Categories: | | | Mol File: | 130007-86-2.mol | ![(S)-TERT-BUTYL 1-(CHLOROMETHYL)-5-HYDROXY-1H-BENZO[E]INDOLE-3(2H)-CARBOXYLATE Structure](CAS/20180528/GIF/130007-86-2.gif) |
| | (S)-TERT-BUTYL 1-(CHLOROMETHYL)-5-HYDROXY-1H-BENZO[E]INDOLE-3(2H)-CARBOXYLATE Chemical Properties |
| Melting point | 161 °C (decomp) | | Boiling point | 493.7±45.0 °C(Predicted) | | density | 1.275±0.06 g/cm3(Predicted) | | storage temp. | -20°C | | form | powder | | pka | 9.63±0.40(Predicted) | | optical activity | [α]/D -89.0, c = 0.05% in chloroform |
| RIDADR | UN 3077 9 / PGIII | | WGK Germany | 3 |
| | (S)-TERT-BUTYL 1-(CHLOROMETHYL)-5-HYDROXY-1H-BENZO[E]INDOLE-3(2H)-CARBOXYLATE Usage And Synthesis |
| Uses | N-Boc-CBI best used as its seco precursor (seco-N-Boc-CBI) is a simple alkylation subunit analog of that found in the naturally occurring antitumor agents the duocarmycins, yatakemycin, and CC-1065, which act by sequence selective DNA alkylation. |
| | (S)-TERT-BUTYL 1-(CHLOROMETHYL)-5-HYDROXY-1H-BENZO[E]INDOLE-3(2H)-CARBOXYLATE Preparation Products And Raw materials |
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