ChemicalBook Product Catalog Chemical Reagents Organic reagents Fatty alcohols 2-(2-Chloroethoxy)ethanol

2-(2-Chloroethoxy)ethanol

2-(2-Chloroethoxy)ethanol Basic information
Product Name:2-(2-Chloroethoxy)ethanol
Synonyms:DIETHYLENE GLYCOL CHLOROHYDRIN;DIETHYLENE GLYCOL MONOCHLOROHYDRIN;ETHYLENE GLYCOL MONO-2-CHLOROETHYL ETHER;2-(2-chloroethoxy)-ethano;2-(2-CHLOROETHOXY)ETHANOL;2-CHLOROETHOXYETHANOL;2-(2-ChL;oroethoxy)ethanoL
CAS:628-89-7
MF:C4H9ClO2
MW:124.57
EINECS:211-059-9
Product Categories:Alkohols;Ethylene Glycols & Monofunctional Ethylene Glycols;Monofunctional Ethylene Glycols;Alcohols;C2 to C6;Oxygen Compounds;Quetiapine
Mol File:628-89-7.mol
2-(2-Chloroethoxy)ethanol Structure
2-(2-Chloroethoxy)ethanol Chemical Properties
Boiling point 79-81 °C5 mm Hg(lit.)
density 1.18 g/mL at 25 °C(lit.)
vapor pressure 22.66Pa at 20℃
refractive index n20/D 1.452(lit.)
Fp 195 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility SOLUBLE
form Liquid
pka14.34±0.10(Predicted)
color Clear
Water Solubility SOLUBLE
BRN 506015
Stability:Stable. Incompatible with strong oxidizing agents.
InChIKeyLECMBPWEOVZHKN-UHFFFAOYSA-N
LogP0.301 at 30℃
CAS DataBase Reference628-89-7(CAS DataBase Reference)
NIST Chemistry ReferenceEthanol, 2-(2-chloroethoxy)-(628-89-7)
EPA Substance Registry SystemEthanol, 2-(2-chloroethoxy)- (628-89-7)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38-36
Safety Statements 26-36-39
RIDADR UN 3334
WGK Germany 2
RTECS KK1350000
F 19
TSCA Yes
HS Code 29094990
MSDS Information
ProviderLanguage
Diethylene glycol monochlorohydrin English
ACROS English
SigmaAldrich English
ALFA English
2-(2-Chloroethoxy)ethanol Usage And Synthesis
Chemical Propertiescolourless liquid
Uses2-(2-Chloroethoxy)ethanol is a degradation product of Bis(2-Chloroethyl) Ether. 2-(2-Chloroethoxy)ethanol is a potential genotoxic impurity (PGI) in active pharmaceutical ingredients (APIs).
Uses2-(2-Chloroethoxy)ethanol is employed in the preparation of o-nitrophenylbromoacetaldehyde bis-2-(2-chloroethoxy)-ethyl acetal, quetiapine and 2-(2-azidoethoxy)ethanol.
Uses2-(2-Chloroethoxy)ethanol was used in the synthesis of o-nitrophenylbromoacetaldehyde bis-2-(2-chloroethoxy)-ethyl acetal, quetiapine (an antipsychotic drug) and 2-(2-azidoethoxy)ethanol.
Flammability and ExplosibilityNonflammable
Diethylene glycol 2-(2-Chloroethoxy)ethanol Diethylene glycol diacrylate Niclosamide ethanolamine salt DIETHOXYMETHANE 1,4-Butanediol Ethoxyquin 2-Methyl-2,4-pentanediol Diethylene glycol monobutyl ether 2-Chloroethanol 2-Ethoxyethanol Ethyl acetate Ethylene glycol 3-Chloro-1,2-propanediol Dipropylene glycol 2-Ethoxyphenol 2-Butoxyethanol Ethoxyethyne
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