6-Aminouracil

6-Aminouracil Basic information
Product Name:6-Aminouracil
Synonyms:4(6)-AMINOURACIL;6-AMINO-2,4-PYRIMIDINEDIOL;6-AMINO-2,4-DIHYDROXY-PYRIMIDINE;6-AMINOURACIL;6-AMINOPYRIMIDINE-2,4(1H,3H)-DIONE;AURORA KA-377;4-AMINOURACIL;4-AMINO-2,6-DIHYDROXYPYRIMIDINE
CAS:873-83-6
MF:C4H5N3O2
MW:127.1
EINECS:212-854-3
Product Categories:Amines;Nucleotides and Nucleosides;PYRIMIDINE;Pyridines, Pyrimidines, Purines and Pteredines;Bases & Related Reagents;Nucleotides;Aromatics;Heterocycles;88/kg;bc0001
Mol File:873-83-6.mol
6-Aminouracil Structure
6-Aminouracil Chemical Properties
Melting point ≥360 °C(lit.)
Boiling point 235.85°C (rough estimate)
density 1.4748 (rough estimate)
refractive index 1.5000 (estimate)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility DMSO (Slightly, Heated), Methanol (Slightly)
pKa3.76±0.10(Predicted)
form Crystalline Powder
color Cream to light brown
Water Solubility slightly soluble
BRN 120491
CAS DataBase Reference873-83-6(CAS DataBase Reference)
EPA Substance Registry System2,4(1H,3H)-Pyrimidinedione, 6-amino- (873-83-6)
Safety Information
Safety Statements 22-24/25
WGK Germany 3
RTECS YQ8750000
10-23
TSCA Yes
HS Code 29335995
ToxicityLDLo par-mus: 2400 mg/kg CBCCT* 7,696,55
MSDS Information
ProviderLanguage
4-Amino-2,6-dihydroxypyrimidine English
ACROS English
SigmaAldrich English
ALFA English
6-Aminouracil Usage And Synthesis
Chemical Propertiescream to light brown crystalline powder
DefinitionChEBI: 6-aminouracil is a pyrimidone.
Safety ProfileModerately toxic by parenteralroute. When heated to decomposition it emits toxic fumesof NOx.
Purification MethodsPurify the aminouracil by dissolving it in 3M aqueous NH3, filtering hot, and adding 3M formic acid until precipitation is complete. Cool, filter off (or centrifuge), wash well with cold H2O, then EtOH and dry it in air. Dry it further in a vacuum at ~80o. [Barlin & Pfeiderer J Chem Soc (B) 1424 1971, Beilstein 25 III/IV 4107.]
6-Aminouracil Preparation Products And Raw materials
Raw materials1,4-Dioxane-->Urea-->Ethyl cyanoacetate
Preparation Products6-methyl-1H-Pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione
4,4'-Diaminodiphenylsulfone Betaine Acetaminophen 6-Aminouracil 4-Hydroxy-6-aminopyrimidine ALTRENOGEST 4,6-Dihydroxypyrimidine 1-Hydroxyethylidene-1,1-diphosphonic acid Sulfamic acid Lithium diisopropylamide Triclosan 4-Aminoantipyrine Iminodiacetic acid Uracil 4-Aminopyrimidine AMINO ACIDS Iminodiacetonitrile N,N-Dimethyl-1,4-phenylenediamine

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