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| | (-)-Corey lactone diol Basic information |
| Product Name: | (-)-Corey lactone diol | | Synonyms: | (-) COREY LACTONE DIOL;(-)-COREY LACTONE DIOL,98%;(3AR,4S,5R,6AS)-(-)-HEXAHYDRO-5-HYDROXY-4--2H-CYCLOPENTA(B)FURAN-2-ONE,;(1R)-2β-(Hydroxymethyl)-3α,5α-dihydroxycyclopentane-1α-acetic acid 1,5-lactone;(1S,5R,6S,7R)-7-Hydroxy-6-hydroxymethyl-2-oxabicyclo[3.3.0]octan-3-one;(3aβ,4S,6aβ)-4β-(Hydroxymethyl)-5α-hydroxyhexahydro-2H-cyclopenta[b]furan-2-one;(-)-6beta-Hydroxymethyl-7alpha-hydroxy-cis-2-oxabicyclo[3.3.0]octan-3-one,98%;(+)-6β-Hydroxymethyl-7α-hydroxy-cis-2-oxabicyclo[3.3.0]octan-3-one | | CAS: | 32233-40-2 | | MF: | C8H12O4 | | MW: | 172.18 | | EINECS: | 608-721-8 | | Product Categories: | Latanoprost;Prostaglandins;API | | Mol File: | 32233-40-2.mol |  |
| | (-)-Corey lactone diol Chemical Properties |
| Melting point | 117-119 °C(lit.) | | Boiling point | 262.49°C (rough estimate) | | density | 1.2104 (rough estimate) | | refractive index | 1.4455 (estimate) | | storage temp. | Sealed in dry,Room Temperature | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | Crystalline Powder or Crystals | | pka | 14.36±0.40(Predicted) | | color | White to beige-brown | | optical activity | [α]20/D 44°, c = 1.4 in methanol | | InChIKey | VYTZWRCSPHQSFX-GBNDHIKLSA-N | | CAS DataBase Reference | 32233-40-2(CAS DataBase Reference) |
| Safety Statements | 24/25 | | WGK Germany | 3 | | HS Code | 29322090 |
| | (-)-Corey lactone diol Usage And Synthesis |
| Chemical Properties | white to beige-brown cryst. powder or crystals | | Uses | (-)-Corey Lactone Diol is an intermediate of Iloprost (I267300) and shows inhibitory activity towards β-lactamase. Iloprost (I267300) is a synthetic analogue of Prostacyclin (PGI2) used to treat pulmo
nary arterial hypertension (PAH), scleroderma, Raynaud's phenomenon and ischemia. | | Uses | (-)-Corey Lactone Diol is an intermediate of Iloprost (I267300) and shows inhibitory activity towards β-lactamase. Iloprost (I267300) is a synthetic analogue of Prostacyclin (PGI2) used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud''s phenomenon and ischemia. | | Definition | ChEBI: (-)-corey lactone is a gamma-lactone. |
| | (-)-Corey lactone diol Preparation Products And Raw materials |
| Raw materials | 2H-Cyclopenta[b]furan-2-one, 5-(acetyloxy)hexahydro-4-(hydroxymethyl)-, (3aR,4S,5R,6aS)--->117624-93-8-->(-)-Corey Lactone Benzoate-->(3aR,4S,5R,6aS)-4-[(Acetyloxy)methyl]hexahydro-5-hydroxy-2H-cyclopenta[b]furan-2-one-->((3aR,4S,6aS)-5-acetoxy-2-oxohexahydro-2H-cyclopenta[b]furan-4-yl)Methyl acetate | | Preparation Products | 2H-Cyclopenta[b]furan-2-one, hexahydro-4-[(1E)-3-oxo-1-octen-1-yl]-5-[(triethylsilyl)oxy]-, (3aR,4R,5R,6aS)--->(+)-Cloprostenol-->2H-Cyclopenta[b]furan-4-carboxaldehyde, hexahydro-5-hydroxy-2-oxo-, (3aR,4R,5R,6aS)--->(3aR,4R,5R,6aS)-Hexahydro-5-hydroxy-4-[(1E)-3-oxo-1-octen-1-yl]-2H-cyclopenta[b]furan-2-one-->(-)-Corey lactone 4-phenylbenzoate alcohol |
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