Sitagliptin Impurity 14

Sitagliptin Impurity 14 Basic information
Product Name:Sitagliptin Impurity 14
Synonyms:3-Amino-4-(2,4,5-trifluorophenyl)butanyl Sitagliptin;Sitagliptin impurity 24/3-Amino-4-(2,4,5-trifluorophenyl)butanyl Sitagliptin/(R)-3-amino-N-((R)-4-oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-yl)-4-(2,4,5-trifluorophenyl)butanamide;(R)-3-amino-N-((R)-4-oxo-4-(3-(trifluoromethyl);Sitagliptin Impurity 18 HCl;Benzenebutanamide, β-amino-N-[(1R)-3-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-oxo-1-[(2,4,5-trifluorophenyl)methyl]propyl]-2,4,5-trifluoro-, (βR)-;(R)-3-amino-N-((R)-4-oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-yl)-4-(2,4,5-trifluorophenyl)butanamide;(R)-3-amino-N-((R)-4-oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-yl)-4-(2,4,5-trifluorophenyl)butanamide? (Sitagliptin Impurity);Benzenebutanamide, β-amino-N-[(1R)-3-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-oxo-1-[(2,4,5-trifluorophenyl)methyl]propyl]-2,4,5-trifluoro-, (βR)-
CAS:2072867-07-1
MF:C26H23F9N6O2
MW:622.5
EINECS:
Product Categories:
Mol File:2072867-07-1.mol
Sitagliptin Impurity 14 Structure
Sitagliptin Impurity 14 Chemical Properties
Melting point >73°C (dec.)
density 1.57±0.1 g/cm3(Predicted)
storage temp. Refrigerator
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form Solid
pka14.55±0.46(Predicted)
color White to Off-White
Safety Information
MSDS Information
Sitagliptin Impurity 14 Usage And Synthesis
Uses3-Amino-4-(2,4,5-trifluorophenyl)butanyl Sitagliptin is an impurity of Sitagliptin (S490990). Sitagliptin is a trizolopyrazine dipeptidyl peptidase IV inhibitor. It has recently been approved for the therapy of type II diabetes.
Sitagliptin Impurity 14 Preparation Products And Raw materials
Benzenebutanoicacid,b-[[(1,1-diMethylethoxy)carbonyl]aMino]-2,4,5-trifluoro-,Methylester,(bR)- (R)-methyl 3-acetamido-4-(2,4,5-trifluorophenyl)butanoate Sitagliptin Impurity 34 Sitagliptin phosphate monohydrate Methyl 3-aMino-4-(2,4,5-trifluorophenyl)butanoate (S)-Sitagliptin Phosphate (R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione (S)-Duloxetine SuccinaMide Methyl 3-acetamido-4-(2,4,5-trifluorophenyl)but-2-enoate 3-THIOPHENEPROPANAMINE, N,N-DIMETHYL-GAMMA-(1-NAPHTHALENYLOXY)-, ETHANEDIOATE(1:1) Sitagliptin EP Impurity B Sitagliptin phosphate Sitagliptin N-Sulfate 7-[(3R)-3-[(N-Acetyl)AMino]-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoroMethyl)-1,2,4-triazolo[4,3-a]pyrazine Sitagliptin Impurity 31 rac-Sitagliptin EP Impurity B HCl Sitagliptin impurity H HCl Sitagliptin

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