Dimethylaminoacetonitrile

Dimethylaminoacetonitrile Basic information
Product Name:Dimethylaminoacetonitrile
Synonyms:N,N-DIMETHYLGLYCINONITRILE;N,N-Dimethylaminoacetonitrile;DIMETHYLAMINOACETONITRILE;DIMETHYLCYANOCACETAMIDE;2-Dimethylaminoacetonitrile;2-(DIMETHYLAMINO)ACETRONITRILE;cyanomethyl(dimethyl)ammonium;(CH3)2NCH2CN
CAS:926-64-7
MF:C4H8N2
MW:84.12
EINECS:213-140-4
Product Categories:Building Blocks;C1 to C5;Chemical Synthesis;Cyanides/Nitriles;Nitrogen Compounds;Organic Building Blocks;Pharmaceutical Intermediates
Mol File:926-64-7.mol
Dimethylaminoacetonitrile Structure
Dimethylaminoacetonitrile Chemical Properties
Melting point 135-138 °C
Boiling point 137-138 °C(lit.)
density 0.863 g/mL at 25 °C(lit.)
vapor pressure 760 mm Hg ( 137 °C)
refractive index n20/D 1.410(lit.)
Fp 98 °F
storage temp. Flammables area
pka5.24±0.28(Predicted)
Water Solubility soluble
BRN 1735677
CAS DataBase Reference926-64-7(CAS DataBase Reference)
NIST Chemistry ReferenceAcetonitrile, (dimethylamino)-(926-64-7)
EPA Substance Registry SystemDimethylaminoacetonitrile (926-64-7)
Safety Information
Hazard Codes T+
Risk Statements 10-25-27-36-23/25
Safety Statements 16-26-28-36/37-45-38-36/37/39-28A
RIDADR UN 2378 3/PG 2
WGK Germany 3
RTECS AL9450000
HazardClass 6.1
PackingGroup II
HS Code 29269095
MSDS Information
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Dimethylaminoacetonitrile English
SigmaAldrich English
ALFA English
Dimethylaminoacetonitrile Usage And Synthesis
Chemical PropertiesClear colourless liquid
DefinitionChEBI: 2-(Dimethylamino)acetonitrile is a tertiary amino compound.
General DescriptionA liquid with a fishlike odor. Flash point 75°F. May be toxic by inhalation and skin absorption. Slightly soluble in water. Used to make other chemicals.
Air & Water ReactionsHighly flammable. Slightly soluble in water.
Reactivity ProfileDimethylaminoacetonitrile has an amine and nitrile group. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. Nitriles may polymerize in the presence of metals and some metal compounds. They are incompatible with acids; mixing nitriles with strong oxidizing acids can lead to extremely violent reactions. Nitriles are generally incompatible with other oxidizing agents such as peroxides and epoxides. The combination of bases and nitriles can produce hydrogen cyanide. Nitriles are hydrolyzed in both aqueous acid and base to give carboxylic acids (or salts of carboxylic acids). These reactions generate heat. Peroxides convert nitriles to amides. Nitriles can react vigorously with reducing agents. Acetonitrile and propionitrile are soluble in water, but nitriles higher than propionitrile have low aqueous solubility. They are also insoluble in aqueous acids.
Health HazardTOXIC; may be fatal if inhaled, ingested or absorbed through skin. Inhalation or contact with some of these materials will irritate or burn skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.
Fire HazardHIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion and poison hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.
Safety ProfilePoison by ingestion, skin contact, and ocular routes. Moderately toxic by inhalation. A skin and eye irritant. A dangerous fire hazard when exposed to heat or flame. When heated to decomposition it emits toxic fumes of NOx and CN-. See also NITRILES.
Dimethylaminoacetonitrile Preparation Products And Raw materials
Preparation Products1,3-Oxazolidine-->SUCCINALDEHYDE
[butyl(methyl)amino]acetonitrile DI-N-PROPYLAMINOACETONITRILE (ETHYLENEDINITRILO)TETRAACETONITRILE N,N-Diethylcyanoacetamide Dimethylaminoacetonitrile 2,2',2''-Nitrilotriacetonitrile 2-PHENYL-2-PIPERIDINOACETONITRILE ALPHA-(4-MORPHOLINO)PHENYLACETONITRILE 4-Dimethylaminobenzaldehyde A-(DIMETHYLAMINO)PHENYLACETONITRILE 2-Dimethylaminoethanol HEXAMETHYLENEIMINOACETONITRILE (1-PYRROLIDINO)ACETONITRILE N,N-Dimethyl-1,4-phenylenediamine N-CYANOMETHYLPIPERIDINE ETHYL-N-BUTYLAMINOACETONITRILE 4-Dimethylaminopyridine (dibutylamino)acetonitrile

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