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Nilotinib Impurity 7

Nilotinib Impurity 7 Basic information
Product Name:Nilotinib Impurity 7
Synonyms:Nilotinib Impurity 7;Nilotinib EP Impurity E;N-(3-(1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl);N-[3-(1H-Imidazol-1-yl)-5-(trifluoromethyl)phenyl]-4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]Benzamide;Benzamide, N-[3-(1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-;N-(3-(1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide;N-(3-(1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide? (Nilotinib Impurity）;Nilotinib Impurity 10 (Nilotinib EP Impurity E)
CAS:2119583-26-3
MF:C27H20F3N7O
MW:515.49
EINECS:
Product Categories:
Mol File:2119583-26-3.mol
Nilotinib Impurity 7 Structure
Nilotinib Impurity 7 Chemical Properties
Melting point >245°C (dec.)
storage temp. Refrigerator
solubility DMSO (Slightly), Methanol (Very Slightly, Heated)
form Solid
color Pale Yellow to Pale Beige
Safety Information
MSDS Information
Nilotinib Impurity 7 Usage And Synthesis
UsesN-[3-(1H-Imidazol-1-yl)-5-(trifluoromethyl)phenyl]-4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]Benzamide, is an imurtiy of Nilotinib (N465300), that might be useful in treatment of chronic myelogenous leukemia.
Nilotinib Impurity 7 Preparation Products And Raw materials
3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzamide Nilotinib impurity 3 Nilotinib Impurity 28 3-Amino-4-methylbenzoic acid Nilotinib Impurity 20 Nilotinib Impurity 1 Nilotinib genotoxic impurity 3 Nilotinib N-Oxide Nilotinib Impurity 10 Methyl 3-amino-4-methylbenzoate Benzenamine, 3-(2-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)- 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzonitrile 1H-IMidazole, 4-Methyl-1-[3-nitro-5-(trifluoroMethyl)phenyl]- 3-[(Aminoiminomethyl)amino]-4-methylbenzoic acid ethyl ester mononitrate 3-(5-Methyl-1H-iMidazol-1-yl)-5-(trifluoroMethyl)benzenaMine 4-Methyl-N-(3-(5-Methyl-1H-iMidazol-1-yl)-5-(trifluoroMethyl)phenyl)-3-((4-(pyridin-3-yl)pyriMidin-2-yl)aMino)benzaMide NILOTINIB IMPURITY 11
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