ARISTOLOCHIC ACID C

ARISTOLOCHIC ACID C Basic information
Product Name:ARISTOLOCHIC ACID C
Synonyms:ARISTOLOCHIC ACID C;Aristolochic Acid Impurity C;ARISTOLOCHIC ACID C(SH);10-Hydroxy-6-nitrophenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid;6-Nitro-10-hydroxyphenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid;Aristolochic acid IIIa;10-hydroxy-6-nitro-naphtho[2,1-g][1,3]benzodioxole-5-carboxylic acid;10-hydroxy-6-nitronaphtho[2,1-g][1,3]benzodioxole-5-carboxylic acid
CAS:4849-90-5
MF:C16H9NO7
MW:327.25
EINECS:
Product Categories:Heterocycles;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals
Mol File:4849-90-5.mol
ARISTOLOCHIC ACID C Structure
ARISTOLOCHIC ACID C Chemical Properties
Melting point 287~292℃
Boiling point 658.7±55.0 °C(Predicted)
density 1.707±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility DMSO (Slightly), Methanol (Slightly, Heated)
pka3.01±0.20(Predicted)
form Solid
color Dark Orange
Water Solubility sparingly soluble in water
Safety Information
MSDS Information
ARISTOLOCHIC ACID C Usage And Synthesis
Chemical PropertiesShiny brown leaflets or a yellow or white powder.
UsesA metabolite of carcinogenic Aristolochic acids (AAs).
DefinitionChEBI: Aristolochic acid C is an aristolochic acid that is phenanthrene-1-carboxylic acid substituted by a methylenedioxy group at the 3,4 positions, by an hydroxy group at position 6, and by a nitro group at position 10. It has a role as a carcinogenic agent, a metabolite, a mutagen, a nephrotoxin and a toxin. It is a C-nitro compound, a member of aristolochic acids, an aromatic ether, a cyclic acetal, a monocarboxylic acid and an organic heterotetracyclic compound.
Potential ExposureAristolochic acids are alkaloids used primarily as a chemical intermediate for pharmaceuticals, lab chemicals, herbal extract, drug.
ShippingUN1544 Alkaloids, solid, n.o.s. or Alkaloid salts, solid, n.o.s. poisonous, Hazard Class: 6.1; Labels: 6.1- Poisonous materials, Technical Name Required. PG III.
IncompatibilitiesCompounds of the carboxyl group react with all bases, both inorganic and organic (i.e., amines) releasing substantial heat, water and a salt that may be harmful. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides.
Waste DisposalIt is inappropriate and possibly dangerous to the environment to dispose of expired or waste drugs and pharmaceuticals by flushing them down the toilet or discarding them to the trash. Household quantities of expired or waste pharmaceuticals may be mixed with wet cat litter or coffee grounds, double-bagged in plastic, discard in trash. Larger quantities shall carefully take into consideration applicable DEA, EPA, and FDA regulations. If possible return the pharmaceutical to the manufacturer for proper disposal being careful to properly label and securely package the material. Alternatively, the waste pharmaceutical shall be labeled, securely packaged and transported by a state licensed medical waste contractor to dispose by burial in a licensed hazardous or toxic waste landfill or incinerator. All federal, state, and local environmental regulations must be observed.
ARISTOLOCHIC ACID C Preparation Products And Raw materials
Aristolochic acid IVa,ARISTOLOCHIC ACID D(RG)(PLEASE CALL) Aristolochic acid B ARISTOLOCHIC ACID A(SH) aristolochic acid E RARECHEM AL BD 0093 1-AMINO-8-NAPHTHOIC ACID 9-AMINOPHENANTHRENE 8-NITRO-NAPHTHALENE-1-CARBOXYLIC ACID ARISTOLOCHIC ACID C 6-methoxynaphthalen-1-amine ARISTOLOCHIC ACID I HPLC GRADE ARISTOLOCHIC ACID A, 7-HYDROXY-(SH) 1,2-DIHYDROXYNAPHTHALENE 4-Methoxy-1-naphthaldehyde 5-Amino-1-naphthol 5-AMINO-2-NAPHTHOL aristolochic acid-Ia ARISTOLOCHIC ACID (I + II)

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