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LCZ Impurity

LCZ Impurity Basic information
Product Name:LCZ Impurity
Synonyms:Sacubitril Impurity 9;LCZ696(Sacubitril/Valsartan) IMP;LCZ Impurity;Sacubitril Impurity 11;Sacubitril Impurity 12;LCZ-696 Impurity 36;Sacubitril Impurity 40;[1,1'-Biphenyl]-4-pentanoic acid, γ-amino-α-methyl-, ethyl ester, (αS,γS)-
CAS:753421-85-1
MF:C20H25NO2
MW:311.43
EINECS:
Product Categories:
Mol File:753421-85-1.mol
LCZ Impurity Structure
LCZ Impurity Chemical Properties
Boiling point 459.1±45.0 °C(Predicted)
density 1.057±0.06 g/cm3(Predicted)
pka9.58±0.42(Predicted)
Safety Information
MSDS Information
LCZ Impurity Usage And Synthesis
LCZ Impurity Preparation Products And Raw materials
(S)-5-[(Biphenyl-4-yl)carbonyl]pyrrolidin-2-one (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpentanoate (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoic acid hydrochloride (R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoic acid Sacubitril Impurity 72 Valsartan AHU-377 2-Pyrrolidinone, 5-([1,1'-biphenyl]-4-ylMethyl)-3-Methyl-, (3R,5S)- sacubitril (2S,4S)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoate AHU-377 (heMicalciuM salt) LCZ696 (S)-5-[(Biphenyl-4-yl)methyl]-1-(2,2-dimethylpropionyl)pyrrolidin-2-one (2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-4-(4-ethoxy-4-oxobutanamido)-2-methylbutanoic acid LCZ696 InteMediate (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate LCZ696 interMediate
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