TiMolol IMpurity E

TiMolol IMpurity E Basic information
Product Name:TiMolol IMpurity E
Synonyms:TiMolol IMpurity E;Timolol EP Impurity E;(Z)-4-[(2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-yl]oxy-4-oxobut-2-enoic acid;Timolol Maleate EP Impurity E;(S)-3-(tert-Butylamino)-1-(4-morpholino-1,2,5-thiadiazol-3-yloxy)propan-2-yl hydrogen maleate;2-Butenedioic acid (2Z)-, 1-[(1S)-1-[[(1,1-dimethylethyl)amino]methyl]-2-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]ethyl] ester;1-?[(1S)?-?1-?[[(1,?1-?Dimethylethyl)?amino]?methyl]?-?2-?[[4-?(4-?morpholinyl)?-?1,?2,?5-?thiadiazol-?3-?yl]?oxy]?ethyl] Ester (2Z)?-?2-?Butenedioic Acid DISCONTINUED;Timolol EP Impurity E/ Timolol Related Compound E
CAS:1026075-53-5
MF:C17H26N4O6S
MW:414.48
EINECS:
Product Categories:
Mol File:1026075-53-5.mol
TiMolol IMpurity E Structure
TiMolol IMpurity E Chemical Properties
Boiling point 618.1±55.0 °C(Predicted)
density 1.300±0.06 g/cm3(Predicted)
pka2.31±0.25(Predicted)
Safety Information
MSDS Information
TiMolol IMpurity E Usage And Synthesis
Uses1-?[(1S)?-?1-?[[(1,?1-?Dimethylethyl)?amino]?methyl]?-?2-?[[4-?(4-?morpholinyl)?-?1,?2,?5-?thiadiazol-?3-?yl]?oxy]?ethyl] Ester (2Z)?-?2-?Butenedioic Acid (Timolol EP Impurity E; Timolol BP Impurity E; Timolol USP Related Compound E) is an impurity of Timolol (T4437005), an adrenergic blocking agent (1); antiarrhythmic (class II); antianginal; antiglaucoma (2) and antihypertensive (3) agent.
TiMolol IMpurity E Preparation Products And Raw materials
Timolol EP Impurity H ((1S,5R,6R)-6-Aminomethyl-3-ethylbicyclo[3.2.0]hept-3-en-6-yl)acetic acid tert-butyl ester Bicyclo[3.2.0]hept-3-ene-6-acetic acid, 6-(aminomethyl)-3-ethyl-, 1,1-dimethylethyl ester, (1R,5S,6S)- 1-Propanol,3-[(1,1-dimethylethyl)amino]-2-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]-oxy]- 4-MORPHOLIN-4-YL-1,2,5-THIADIAZOL-3-OL (S)-Timolol maleate (+)-1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol Timolol 3-Chloro-4-morpholino-1,2,5-thiadiazole Timolol EP Impurity G

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