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| | Grela 2nd Generation Basic information | | Reaction |
| Product Name: | Grela 2nd Generation | | Synonyms: | RutheniuM, [1,3-bis(2,4,6-triMethylphenyl)-2-iMidazolidinylidene]dichloro[[2-(1-Methylethoxy-κO)-5-nitrophenyl]Methylene-κC]-, (SP-5-41)-;[1,3-bis (2,4,6-trimethylphenyl) -2- imidazolidinylidene] (2-isopropoxy-5-nitrophenyl methylene) ruthenium dichloride;nitro-Grela;(SP-5-41)-[1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro[[2-(1-methylethoxy-kO)-5-nitrophenyl]Methylene-kC]-ruthenium;Grela nitro-Grela;1,3-bis(2,4,6-trimethylphenyl)imidazolidin-2-ylidene]-dichloro-[(5-nitro-2-propan-2-yloxyphenyl)methylidene]ruthenium;Grela's catalyst;Grela 2 | | CAS: | 502964-52-5 | | MF: | C31H36Cl2N3O3Ru | | MW: | 670.62 | | EINECS: | | | Product Categories: | | | Mol File: | 502964-52-5.mol |  |
| | Grela 2nd Generation Chemical Properties |
| Melting point | >300 °C | | storage temp. | 2-8°C | | form | Powder | | color | green | | CAS DataBase Reference | 502964-52-5 |
| | Grela 2nd Generation Usage And Synthesis |
| Reaction |
- This catalyst is used for an efficient synthesis of HCV Protease Inhibitor, BILN 2061.
- The nitro-Grela catalyst is a stable olefin metathesis initiator active in various ring-closing, cross, and enyne metathesis reactions. Its efficiency has been proven in numerous total syntheses of natural and biologically active compounds, and in material science.
| | Uses | nitro-Grela is a universal catalyst which provides good results in a wide spectrum of olefin metathesis transformations. The catalyst provides high efficiency in cross metathesis (CM) reactions between type 1 olefins and an electron deficient partner. The catalyst is very good for CM of disubstituted internal olefins. |
| | Grela 2nd Generation Preparation Products And Raw materials |
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