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Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloro Dasatinib

Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloro Dasatinib Basic information
Product Name:Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloro Dasatinib
Synonyms:Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloro Dasatinib;Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloro Dasatinib/N-[2-Chloro-6-(hydroxymethyl)phenyl]-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide;5-Thiazolecarboxamide, N-[2-chloro-6-(hydroxymethyl)phenyl]-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-
CAS:910297-71-1
MF:C16H13Cl2N5O2S
MW:410.28
EINECS:
Product Categories:Intermediates & Fine Chemicals;Pharmaceuticals;Tyrosine Kinase Inhibitors
Mol File:910297-71-1.mol
Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloro Dasatinib Structure
Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloro Dasatinib Chemical Properties
Melting point 237-240°C
density 1.593±0.06 g/cm3(Predicted)
storage temp. Refrigerator
solubility DMSO (Slightly), Methanol (Slightly)
pka10.69±0.70(Predicted)
form Solid
color Pale Beige
Safety Information
MSDS Information
Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloro Dasatinib Usage And Synthesis
UsesIntermediate in the preparation of Dasatinib metabolite, used in the treatment of cancers and immune diseases. It is a COVID19-related research product.
UsesIntermediate in the preparation of Dasatinib metabolite, Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloro Dasatinib is used in the treatment of cancers and immune diseases.
Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloro Dasatinib Preparation Products And Raw materials
Hydroxymethyl Dasatinib N-Deshydroxyethyl Dasatinib Dasatinib Carboxylic Acid 2-(4-(6-((5-((2-chloro-6-Methylphenyl)carbaMoyl)thiazol-2-yl)aMino)-2-MethylpyriMidin-4-yl)piperazin-1-yl)ethyl acetate Dasatinib DiMeric IMpurity N-Deshydroxyethyl Dasatinib-d8 2’-Deschloro-2’-hydroxy Dasatinib Dasatinib N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide N-(2-Chloro-4-hydroxy-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloro-O-pivalate Dasatinib 2-Amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide Dasatinib N-Oxide 4-[6-[[5-[[(2-Chloro-6-Methylphenyl)aMino]carbonyl]-2-thiazolyl]aMino]-2-Methyl-4-pyriMidinyl]-1-piperazineacetic Acid Ethyl Ester Dasatinib-d8 Dasatinib iMpurity (E)-N-(2-Chloro-6-methylphenyl)-3-ethoxyacrylamide
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