Benzylparaben

Benzylparaben Basic information
Product Name:Benzylparaben
Synonyms:4-Hxdroxybenzoic acid benzyl ester;4-HYDROXYBENZOIC ACID BENZYL ESTER;BASEPTOL;BENZYLPARABEN;BENZYL P-HYDROXYBENZOATE;BENZYL 4-HYDROXYBENZOATE;Benzoicacid,4-hydroxy-,phenylmethylester;Benzyl Parasept
CAS:94-18-8
MF:C14H12O3
MW:228.24
EINECS:202-311-9
Product Categories:Aromatics;Color Former & Related Compounds;Aromatic Esters;Developer;Functional Materials
Mol File:94-18-8.mol
Benzylparaben Structure
Benzylparaben Chemical Properties
Melting point 109-112 °C(lit.)
Boiling point 170℃
density 1.1799
vapor pressure 0Pa at 25℃
refractive index 1.5805
Fp 167℃
storage temp. Inert atmosphere,2-8°C
solubility ethanol: soluble25mg/mL, clear, colorless
pka8.18±0.15(Predicted)
form Powder
color White to Almost white
Water Solubility 92mg/L(25 ºC)
BRN 2115995
LogP2.185 at 25℃
CAS DataBase Reference94-18-8(CAS DataBase Reference)
NIST Chemistry ReferenceBenzyl 4-hydroxybenzoate(94-18-8)
EPA Substance Registry SystemBenzoic acid, 4-hydroxy-, phenylmethyl ester (94-18-8)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-37/39
RIDADR 3077
WGK Germany 3
RTECS DH2691000
TSCA Yes
HazardClass IRRITANT
PackingGroup III
HS Code 29181990
MSDS Information
ProviderLanguage
Benzyl paraben English
ACROS English
SigmaAldrich English
ALFA English
Benzylparaben Usage And Synthesis
Chemical Propertieswhite to light yellow fine powder
UsesAn antimicrobial
Usespreservative in cosmetics and pharmaceutical preparations
UsesBenzyl 4-hydroxybenzoate may be used as internal standard for the simultaneous analysis of non-steroidal anti-inflammatory drugs in human plasma and urine using microextraction by packed sorbent and HPLC method. It may be employed as internal standard for the HPLC determination of rutin, kaempferol, genistein, formononetin and biochanin A in Ononis spinosu roots.
DefinitionChEBI: Benzyl parahydroxybenzoate is a benzoate ester and a benzyl ester.
General DescriptionBenzyl 4-hydroxybenzoate (Paraben, Benzyl Paraben) is an ester of para-hydroxy benzoic acid. It has been added to various cosmetics and personal care products as a preservative. Its quantification in cosmetics has been reported by HPLC methods. Microwave assisted synthesis of benzyl 4-hydroxybenzoate by reaction between (4-hydroxybenzoic) acid and K2CO3 in presence of phase transfer catalyst has been reported. It is an endocrine disrupting chemical (EDC). It is a promising candidate for use in pharmaceutical and personal care products. Its visible-light assisted photosensitized degradation in homogeneous aqueous solution of 4,4′,4′′,4′′′-(porphine-5,10,15,20-tetrayl)tetrakis(benzenesulphonic acid) has been investigated.
Flammability and ExplosibilityNotclassified
Contact allergensThis substance is one of the parabens family. Parabens are esters formed by p-hydroxybenzoic acid and an alcohol. They are largely used as biocides in cosmetics and toiletries, medicaments, or food. They have synergistic power with other biocides. Parabens can induce allergic contact dermatitis, mainly in chronic dermatitis and wounded skin.
Benzylparaben Preparation Products And Raw materials
Preparation Products4-dodecanoyloxybenzoic acid
Methylparaben Benzoyl peroxide 4-Hydroxybenzoic acid Benzyl chloride Sodium methylparaben 2'-Hydroxy-3-phenylpropiophenone Benzyl alcohol Methyl 4-cyanobenzoate Butylparaben Methyl 4-methylbenzoate Isopropylparaben Methyl 4-(bromomethyl)benzoate Benzyl Benzyl acetate Methyl salicylate Benzyl benzoate Heptyl 4-hydroxybenzoate 4-Hydroxybenzhydrazide

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