ChemicalBook Product Catalog Biochemical Engineering Saccharides Monosaccharide 4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOPYRANOSIDE HYDRATE

4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOPYRANOSIDE HYDRATE

4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOPYRANOSIDE HYDRATE Basic information
Product Name:4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOPYRANOSIDE HYDRATE
Synonyms:4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOPYRANOSIDE;4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOPYRANOSIDE HYDRATE;4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOSIDE;4-METHYLUMBELLIFERYL A-D-GLUCOPYRANOSIDE;4-methyl-2-oxo-2H-chromen-7-yl-α-L-galactopyranoside;4-MethyluMbelliferyl α-D-Glucose;4-Methyl-7-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxyMethyl)tetrahydro-2H-pyran-2-yl)oxy)-2H-chroMen-2-one;4-MethyluMbellifery -α-D-glucoside
CAS:17833-43-1
MF:C16H18O8
MW:338.31
EINECS:241-794-0
Product Categories:substrate;Substrates;13C & 2H Sugars;Carbohydrates & Derivatives;Fluorescent Labels & Indicators;Labeling and Diagnostics Reagents
Mol File:17833-43-1.mol
4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOPYRANOSIDE HYDRATE Structure
4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOPYRANOSIDE HYDRATE Chemical Properties
Melting point 171-173 °C
Boiling point 626.9±55.0 °C(Predicted)
density 1.522±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: 50 mg/mL, clear, colorless to faintly yellow
pka12.73±0.70(Predicted)
form White solid
color White to Off-White
BRN 1690776
InChIKeyYUDPTGPSBJVHCN-JZYAIQKZSA-N
CAS DataBase Reference17833-43-1(CAS DataBase Reference)
Safety Information
Safety Statements 22-24/25
WGK Germany 3
F 3-10-21
HS Code 2932209090
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOPYRANOSIDE HYDRATE Usage And Synthesis
Description4-Methylumbelliferyl-α-D-glucopyranoside is a fluorogenic substrate for α-glucosidase. 4-Methylumbelliferyl-α-D-glucopyranoside is cleaved by α-glucosidase to release the fluorescent moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high pH (7.12-10.3), respectively, and an emission maximum ranging from 445 to 455 nm, increasing as pH decreases. 4-Methylumbelliferyl-α-D-glucopyranoside has been used to quantify α-glucosidase activity in infant blood spot samples as a biomarker of Fabry and Pompe diseases, lysosomal storage disorders characterized by a deficiency in the enzyme.
Chemical Propertieswhite to off-white crystalline powder
Uses4-Methylumbelliferyl-α-D-glucopyranoside is a fluorogenic substrate in the assay of a-glucosidase,it has been used in the study of Pompe disease.
Uses4-Methylumbelliferyl α-D-glucopyranoside is used as a flurogenic substrate for the identification, characterization and kinetic analysis of α-D-glucosidase(s).
DefinitionChEBI: 4-Methylumbelliferyl-alpha-D-glucopyranoside is a member of coumarins and a glycoside.
Purification MethodsRecrystallise 4-methylumbellifer-7-yl--D-glucopyranoside from hot H2O or EtOH. [Courtin-Duchateau & Veyrière Carbohydr Research 65 23, 29 1978, Beilstein 18 IV 443.]
4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOPYRANOSIDE HYDRATE Preparation Products And Raw materials
Raw materials4-Methylumbelliferyl2,3,4,6-tetra-O-acetyl-a-D-glucopyranoside
4-METHYLUMBELLIFERYL SULFATE POTASSIUM SALT 4-Methylumbelliferyl 2-Sulfamino-2-deoxy-α-D-glucopyranoside Sodium Salt 4-Methylumbelliferyl b-D-glucosaminide 4-methyl-2-oxo-2H-1-benzopyran-7-yl alpha-L-ido-pyranosiduronic acid 4-METHYLUMBELLIFERYL-BETA-D-CELLOBIOPYRANOSIDE 4-METHYLUMBELLIFERYL-BETA-D-XYLOPYRANOSIDE 4-Methylumbelliferylbeta-D-ribofuranoside 4-Methylumbelliferyl α-L-idopranosiduronic acid 2-sulphate sodium salt (4-Methylumbelliferyl)-N-acetyl-α-D-neuraminic acid sodium salt 4-METHYLUMBELLIFERYL-BETA-D-LACTOSIDE 4-Methylumbelliferyl-beta-D-glucopyranoside 4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOPYRANOSIDE HYDRATE PHENYL ALPHA-D-GLUCOPYRANOSIDE 4-Methylumbelliferyl2,3,4,6-tetra-O-acetyl-a-D-glucopyranoside
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