4-Methoxyfuro[2,3-b]quinolin-8-ol

4-Methoxyfuro[2,3-b]quinolin-8-ol Basic information
Product Name:4-Methoxyfuro[2,3-b]quinolin-8-ol
Synonyms:4-Methoxyfuro[2,3-b]quinolin-8-ol;Robustine;8-Hydroxydictamnine;NPLC 0314;Robustine (Haplophyllum);8-hydroxy dictanmnine;Furo[2,3-b]quinolin-8-ol, 4-methoxy-;alkaloid,phosphodiesterase,Phosphodiesterase (PDE),Robustine,PDE5A,inhibit,Inhibitor
CAS:2255-50-7
MF:C12H9NO3
MW:215.2
EINECS:
Product Categories:Alkaloids
Mol File:2255-50-7.mol
4-Methoxyfuro[2,3-b]quinolin-8-ol Structure
4-Methoxyfuro[2,3-b]quinolin-8-ol Chemical Properties
Melting point 148-149℃ (ethanol )
Boiling point 411.9±40.0 °C(Predicted)
density 1.378±0.06 g/cm3(Predicted)
storage temp. 4°C, protect from light
pka5.34±0.30(Predicted)
Safety Information
MSDS Information
4-Methoxyfuro[2,3-b]quinolin-8-ol Usage And Synthesis
DescriptionHaplophyllum robustum Bge. yields this alkaloid which forms colourless crystals from EtOH. It forms a series of crystalline salts and derivatives including the hydrochloride, m.p. 199-200°C; picrate, m.p. I 79-180°C; acetyl derivative, m.p.174-5°C; methyl derivative, m.p. 140-2°C and the tetrahydrG compound with m.p.201-2°C.
DefinitionChEBI: A quinoline alkaloid that is furo[2,3-b]quinoline substituted by a methoxy and a hydroxy group at positions 4 and 8 respectively.
ReferencesFakhritdinova, Sidyakin, Yunusov,Khim. Prir.Soedin., 1, 107 (1965)
Faizutdinova, Yunusov, ibid, 3, 260 (1967)
Narasimhan, Paradkar, Alurkar, Tetrahedron, 27,1351 (1971)

4-Methoxyfuro[2,3-b]quinolin-8-ol Preparation Products And Raw materials
Daurinoline Xanthiazone DICTAMNINE veratramine VERATRIDINE gamma-fagarine Xanthiside Butyl stearate FRAXINELLONE L-Hyoscyamine daurisoline 2-[2-(Methylamino)benzoyl]-3,4-dihydro-β-carboline-1(2H)-one VERATRINE menisdaurin OBACUNON

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