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| | BIS(2-CHLOROISOPROPYL)ETHER Basic information |
| Product Name: | BIS(2-CHLOROISOPROPYL)ETHER | | Synonyms: | (2-Chloro-1-methylethyl) ether;(2-chloro-1-methylethyl)ether;1-Chloro-2-(2-chloro-1-methylethoxy)propane;2,2’-dichlorodiisopropylether;2,2’-dichloroisopropylether;2,2’-oxybis(1-chloro-propan;2,2’-oxybis(1-chloropropane);2,2’-oxybis[1-chloro-propan | | CAS: | 108-60-1 | | MF: | C6H12Cl2O | | MW: | 171.06 | | EINECS: | 203-598-3 | | Product Categories: | | | Mol File: | 108-60-1.mol |  |
| | BIS(2-CHLOROISOPROPYL)ETHER Chemical Properties |
| Melting point | -97℃ | | Boiling point | 242.21°C (rough estimate) | | density | 1.1030 | | vapor pressure | 0.56 (quoted, Kawamoto and Urano, 1989) | | refractive index | 1.4505 (estimate) | | Fp | 11 °C | | storage temp. | 0-6°C | | solubility | Soluble in acetone, ethanol, benzene, ether (Weast, 1986), and many other solvents including
methanol, propanol, and 2-butanone. | | form | neat | | Henry's Law Constant | 0.24 at 25 °C (static headspace-GC, Kawamoto and Urano, 1989) | | Exposure limits | No exposure limit is set for this compound. Carcinogen — Animal Limited Evidence (IARC). | | CAS DataBase Reference | 108-60-1 | | IARC | 3 (Vol. 41, Sup 7, 71) 1999 | | EPA Substance Registry System | Bis(2-chloro-1-methylethyl) ether (108-60-1) |
| | BIS(2-CHLOROISOPROPYL)ETHER Usage And Synthesis |
| Description | Bis-(2-chloroisopropyl) ether is a byproduct in the synthesis of ethylene and propylene glycol that has been found in municipal drinking water in the United States and waterways in the Netherlands where it is considered a persistent organic pollutant (POP). It is mutagenic in the S. typhimurium strains TA 1535 and TA 100 but lacks mutagenic activity in mice. | | Chemical Properties | Clear Colourless Oil | | Chemical Properties | Dichloroisopropyl ether is a colorless liquid. | | Physical properties | Colorless to light brown oily liquid. Verschueren (1983) reported an odor threshold concentration
of 320 ppb. | | Uses | Bis(2-chloroisopropyl)ether is used as a sol vent for resins, waxes, and oils, and inorganic synthesis. | | Uses | Apparently used as a nematocide in Japan but is not registered in the U.S. for use
as a pesticide. | | Uses | Bis(2-chloroisopropyl) Ether is an organochlorine pesticide. Bis(2-chloroisopropyl) Ether is used as a nematicide to control parasitic nematodes in agriculture. | | Definition | ChEBI: Bis(2-chloro-1-methylethyl)ether is an ether. | | General Description | Colorless to light brown liquid. Odor threshold concentration 200 μg/L. | | Air & Water Reactions | Subject to peroxidation in air. Insoluble in water. | | Reactivity Profile | BIS(2-CHLOROISOPROPYL)ETHER oxidizes readily in air to form unstable peroxides that may explode spontaneously [Bretherick 1979 p.151-154, 164]. | | Health Hazard | Bis(2-chloroisopropyl)ether exhibited moderately toxic and carcinogenic actions intest animals. The acute inhalation toxicity of this compound is considerably lowerthan those of bis(chloromethyl)ether and bis(chloroethyl)ether. Exposure to its vapors cancause irritation of the eyes and upper respiratory tract. Inhalation of 700 ppm of this com pound in air for 5 hours proved fatal to rats
The oral toxicity of bis(2-chloroisopropyl)ether in rats was found to be moderate, withan LD50 value of 240 mg/kg.
The compound is carcinogenic to animals.Although there is no evidence of its carcino genicity in humans, exposure may cause lungcancer. | | Fire Hazard | BIS(2-CHLOROISOPROPYL)ETHER is combustible. | | Potential Exposure | BCIE was previously used as a solvent
and as an extractant. It may be formed as a by-product of
propylene oxide production. It has been found in industrial
waste water and in natural water. | | Source | No MCLGs or MCLs have been proposed, however, a DWEL of 1
mg/L was recommended (U.S. EPA, 2000).
A waste by-product in the manufacture of propylene glycol (quoted, Verschueren, 1983). | | Environmental Fate | Biological. When bis(2-chloroisopropyl)ether (5 and 10 mg/L) was statically incubated
in the dark at 25°C with yeast extract and settled domestic wastewater inoculum, complete
biodegradation was achieved after 14 days (Tabak et al., 1981).
Chemical/Physical. Kollig (1993) reported that bis(2-chloroisopropyl)ether is subject
to hydrolysis forming hydrochloric acid and the intermediate (2-hydroxy-isopropyl-2-
chloroisopropyl)ether. The latter undergoes further hydrolysis yielding bis | | Shipping | UN2490 Dichloroisopropyl ether, Hazard Class:
6.1; Labels: 6.1—Poisonous materials. | | Incompatibilities | Incompatible with oxidizers (chlorates,
nitrates, peroxides, permanganates, perchlorates, chlorine,
bromine, fluorine, etc.); contact may cause fires or explosions.
Keep away from alkaline materials, strong bases,
strong acids, oxoacids, epoxides. It may form dangerous
peroxides upon standing; may explode when heated. | | Waste Disposal | Use special incinerator due to
high HCl content, such as seagoing incinerator ships. |
| | BIS(2-CHLOROISOPROPYL)ETHER Preparation Products And Raw materials |
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