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4'-hydroxyflurbiprofen

4'-hydroxyflurbiprofen Basic information
Product Name:4'-hydroxyflurbiprofen
Synonyms:(1,1'-Biphenyl)-4-acetic acid, 2-fluoro-4'-hydroxy-alpha-methyl-;2-(4'-Hydroxy-2-fluoro-4-biphenylyl)propionic Acid;2-Fluoro-4'-hydroxy-α-Methyl-[1,1'-biphenyl]-4-acetic Acid;FPH;Flurbiprofen EP Impurity G;2-(2-fluoro-4'-hydroxy-[1,1'-biphenyl]-4-yl)propanoic acid;Flurbiprofen 4-Hydroxy;[1,1'-Biphenyl]-4-acetic acid, 2-fluoro-4'-hydroxy-α-methyl-
CAS:52807-12-2
MF:C15H13FO3
MW:260.26
EINECS:
Product Categories:Aromatics;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals
Mol File:52807-12-2.mol
4'-hydroxyflurbiprofen Structure
4'-hydroxyflurbiprofen Chemical Properties
Melting point 177-178°C
Boiling point 417.6±40.0 °C(Predicted)
density 1.288±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility DMF: 25 mg/ml; DMSO: 10 mg/ml; Ethanol: 25 mg/ml; PBS (pH 7.2): 0.5 mg/ml
form A crystalline solid
pka4.20±0.10(Predicted)
Safety Information
MSDS Information
4'-hydroxyflurbiprofen Usage And Synthesis
Chemical PropertiesWhite to Off-White Solid
Uses4'-hydroxyflurbiprofen is a metabolite of Flurbiprofen (F598700), an anti-inflammatory used as an analgesic.
DefinitionChEBI: 4'-Hydroxyflurbiprofen is a member of biphenyls.
4'-hydroxyflurbiprofen Preparation Products And Raw materials
2,4-Difluoronitrobenzene flurbiprofen 4-Acetyl-2-fluorobiphenyl Flurbiprofen Impurity 8 Flurbiprofen Impurity 15 Methyl Flurbiprofen 2,4-Difluorobiphenyl 2-Fluorobiphenyl-4-carboxylic Acid Flurbiprofen Impurity Flurbiprofen Related Impurity 1 4-ETHYL-2-FLUORO-1,1'-BIPHENYL (2-FLUORO-4-BIPHENYL)ACETIC ACID α-Hydroxy Flurbiprofen Flurbiprofen Related Impurity 2 Flurbiprofen EP Impurity M Flurbiprofen 4'-hydroxyflurbiprofen 2-(4'-ACETOXY-2-FLUORO-BIPHENYL-4-YL)-PROPIONATE
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