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| | 5,6-DIHYDROURACIL Basic information |
| Product Name: | 5,6-DIHYDROURACIL | | Synonyms: | TIMTEC-BB SBB007702;2,4(1H,3H)-Pyrimidinedione, dihydro-;3h)-pyrimidinedione,dihydro-4(1h;Dihydro-pyrimidine-2,4-dione;Hydrouracil;5,6-DIHYDROURACIL;5,6-DIHYDRO-2,4-DIHYDROXYPYRIMIDINE;DIHYDRO-2,4(1H,3H)-PYRIMIDINEDIONE | | CAS: | 504-07-4 | | MF: | C4H6N2O2 | | MW: | 114.1 | | EINECS: | 207-982-1 | | Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals;Nucleic acids | | Mol File: | 504-07-4.mol |  |
| | 5,6-DIHYDROURACIL Chemical Properties |
| Melting point | 279-281 °C (lit.) | | Boiling point | 213.59°C (rough estimate) | | density | 1.3565 (rough estimate) | | refractive index | 1.4487 (estimate) | | storage temp. | 2-8°C | | solubility | Soluble in Sodium Hydroxide. | | form | Solid | | pka | 12.10±0.20(Predicted) | | color | White to Light Beige | | BRN | 112496 | | InChI | InChI=1S/C4H6N2O2/c7-3-1-2-5-4(8)6-3/h1-2H2,(H2,5,6,7,8) | | InChIKey | OIVLITBTBDPEFK-UHFFFAOYSA-N | | SMILES | C1(=O)NCCC(=O)N1 | | CAS DataBase Reference | 504-07-4(CAS DataBase Reference) | | EPA Substance Registry System | 2,4(1H,3H)-Pyrimidinedione, dihydro- (504-07-4) |
| Safety Statements | 24/25 | | WGK Germany | 3 | | TSCA | Yes |
| | 5,6-DIHYDROURACIL Usage And Synthesis |
| Chemical Properties | white to light beige crystalline powder | | Uses | Impurity of Uracil. | | Uses | 5,6-Dihydrouracil acts as an intermediate in the catabolism of uracil. | | Uses | Dihydrouracil has been used as a standard for ureido group in the colorimentric assay of transfer ribonucleic acid (tRNA). | | Definition | ChEBI: 5,6-dihydrouracil is a pyrimidine obtained by formal addition of hydrogen across the 5,6-position of uracil. It has a role as a metabolite, a human metabolite, an Escherichia coli metabolite and a mouse metabolite. It is functionally related to a uracil. | | General Description | Dihydrouracil (DiHU) is a minor base found in transfer ribonucleic acid (tRNA). It is similar to uracil with the only exception that the C5-C6 bond is saturated. It crystallized in the monoclinic system with space group P21/C. Its crystalline structure has been analyzed. Its generation from L-cysteine and uracil via photochemical addition has been described. |
| | 5,6-DIHYDROURACIL Preparation Products And Raw materials |
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