BOC-HYP-OL

BOC-HYP-OL Basic information
Product Name:BOC-HYP-OL
Synonyms:TERT-BUTYL (2S,4R)-4-HYDROXY-2-(HYDROXYMETHYL)PYRROLIDINE-1-CARBOXYLATE;(-)-N-BOC-L-4-HYDROXYPROLINOL;N-BOC-TRANS-4-HYDROXY-L-PROLINOL;N-T-BUTOXYCARBONYL-TRANS-4-HYDROXY-L-PROLINOL;BOC-HYP-OL;BOC-PRO(4-HYDROXY)-OL;BOC-TRANS-4-HYDROXY-L-PROLINOL;1-Pyrrolidinecarboxylic acid, 4-hydroxy-2-(hydroxymethyl)-, 1,1-dimethylethyl ester, (2S,4R)-
CAS:61478-26-0
MF:C10H19NO4
MW:217.26
EINECS:
Product Categories:Amino Acid Derivatives;Amino Alcohols;Peptide Synthesis
Mol File:61478-26-0.mol
BOC-HYP-OL Structure
BOC-HYP-OL Chemical Properties
Melting point 81-86 °C (lit.)
alpha -47o (C=1 IN CHLOROFORM)
Boiling point 340.3±27.0 °C(Predicted)
density 1.190±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
pka14.57±0.40(Predicted)
color White
optical activity[α]20/D 47°, c = 1 in chloroform
Sensitive Air Sensitive
CAS DataBase Reference61478-26-0(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-37
WGK Germany 3
HazardClass IRRITANT
HS Code 29339900
MSDS Information
ProviderLanguage
SigmaAldrich English
BOC-HYP-OL Usage And Synthesis
Chemical PropertiesViscous Oil
UsesBOC-HYP-OL is a useful reactant used in the preparation of 4-purinylpyrrolidine nucleosides, kinase inhibitors and antibacterial agents.
BOC-HYP-OL Preparation Products And Raw materials
Preparation Products2-PyrrolidineMethanol, 4-hydroxy-, hydrochloride (1:1), (2S,4R)--->1-Pyrrolidinecarboxylic acid, 2-(hydroxymethyl)-4-methyl-, 1,1-dimethylethyl ester, (2S,4S)--->(2S,4R)-tert-butyl 2-(((tert-butyldimethylsilyl)oxy)methyl)-4-hydroxypyrrolidine-1-carboxylate-->(3S,5R)-4-Hydroxy-2-pyrrolidinemethanol
BOC-HYP-OL (2S,4S)-1-(TERT-BUTOXYCARBONYL)-4-(2-NAPHTHYLOXY)-2-PYRROLIDINECARBOXYLIC ACID BOC-L-TRANSPRO(OTS)-OBN 4-(TERT-BUTYL-DIMETHYL-SILANYLOXY)-2-HYDROXYMETHYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER N-Boc-trans-4-tosyloxy-L-proline methyl ester 4-HYDROXY-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 2-METHYL ESTER N-Boc-cis-4-Hydroxy-L-proline (2S,4R)-BOC-4-(2-NAPHTHYLOXY)-PYRROLIDINE-2-CARBOXYLIC ACID BOC-HYP-OTBU (2S,4S)-1-(TERT-BUTOXYCARBONYL)-4-PHENOXY-2-PYRROLIDINECARBOXYLIC ACID BOC-HYP(BZL)-OH BOC-HYP-OBZL AKOS 338 4(R)-T-BUTYLDIMETHYLSILYLOXY-N-BOC-2(S)PROLINOL BOC-HYP-OH DCHA (2S,4R)-BOC-4-(2-NAPHTHYLMETHOXY)-PYRROLIDINE-2-CARBOXYLIC ACID 4-(TERT-BUTYL-DIMETHYL-SILANYLOXY)-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER (2S,4R)-BOC-4-PHENOXY-PYRROLIDINE-2-CARBOXYLIC ACID

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