3-acetamidophthalic acid

3-acetamidophthalic acid Basic information
Product Name:3-acetamidophthalic acid
Synonyms:3-acetamidophthalic acid;3-(Acetylamino)phthalic acid;1,2-Benzenedicarboxylic acid, 3-(acetylamino)-;3-Acetamido-1,2-benzenedicarboxylic acid;Einecs 239-404-9;Apremilast Impurity B;Apremilast EP Impurity B;Apremilast Impurity 14(Apremilast EP Impurity B)
CAS:15371-06-9
MF:C10H9NO5
MW:223.18
EINECS:239-404-9
Product Categories:
Mol File:15371-06-9.mol
3-acetamidophthalic acid Structure
3-acetamidophthalic acid Chemical Properties
Melting point 260 °C
Boiling point 518.2±45.0 °C(Predicted)
density 1.512±0.06 g/cm3(Predicted)
storage temp. Refrigerator, under inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka2.54±0.10(Predicted)
color Pale Yellow
EPA Substance Registry System3-(Acetylamino)phthalic acid (15371-06-9)
Safety Information
MSDS Information
3-acetamidophthalic acid Usage And Synthesis
Uses3-Acetamidophthalic Acid is an impurity of Apremilast (A729700); an oral phosphodiesterase 4 inhibitor used in the treatment of psoriatic arthritis. Apremilast EP Impurity B
3-acetamidophthalic acid Preparation Products And Raw materials
3-Ethoxy-4-methoxybenzaldehyde oxime Apremilast (S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide HHUBRUYPYDODRB-UHFFFAOYSA-N Apremilast Impurity G Apremilast Apremilast Impurity FA 3-Ethoxy-4-Methoxy-alpha-[(Methylsulfonyl)Methyl]-benzeneMethanaMine 1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl) ethanone (S)-N-(2-(1-(3,4-dihydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide 1-(3,4-Dimethoxyphenyl)-2-(methylsulfonyl)ethan-1-amine (E)-3-hydroxy-4-methoxybenzaldehyde oxime 1,2-Benzenedicarboxylicacid,3-(hydroxyamino)-(9CI) Apremilast 3-ETHOXY-4-METHOXYBENZOIC ACID Apremilast Apremilast Impurity 1 Apremilast Impurity E

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