ChemicalBook Product Catalog API Nervous system drugs Antipsychotics (R)-Duloxetine

(R)-Duloxetine

(R)-Duloxetine Basic information
Product Name:(R)-Duloxetine
Synonyms:(r)-duloxetine;(r)-n-methyl-gama-(1-naphthalenyloxy)-2-thiophenepropanamine;R-DULOXETINE HCL;(R)-N-Methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-aMine hydrochloride;N-methyl-3-(1-naphthalenyloxy)-3-thiophen-2-yl-1-propanamine;Ariclaim;CYMBALTA; ARICLAIM;2-Thiophenepropanamine, N-methyl-γ-(1-naphthalenyloxy)-, (γR)
CAS:116539-60-7
MF:C18H19NOS
MW:297.41
EINECS:1312995-182-4
Product Categories:Pharmaceutical intermediate
Mol File:116539-60-7.mol
(R)-Duloxetine Structure
(R)-Duloxetine Chemical Properties
Boiling point 466.2±40.0 °C(Predicted)
density 1.158
pka10.02±0.10(Predicted)
Safety Information
MSDS Information
(R)-Duloxetine Usage And Synthesis
Uses(R)-Duloxetine is a dual inhibitor of serotonin and norepinephrine reuptake, effective in the treatment of emotional and physical symptoms of depression
DefinitionChEBI: (R)-duloxetine is a duloxetine. It is an enantiomer of a (S)-duloxetine.
ApplicationDuloxetine (duloxetine) is a third-generation antidepressant launched in 2002, and its hydrochloride is clinically used under the trade name Cymbalta (Cymbalta).
Synthesis(R)-Duloxetine was prepared from (S)-3-N,N-dimethylamino-1-(2-thienyl)-1-propanol 67.
(R)-Duloxetine Preparation Products And Raw materials
Preparation Products(±)-Duloxetine
Methyl R-DULOXETINE HYDROCHLORIDE DULOXETINE-NAPHTHYL-D7 Intermediate Of Duloxetine Hcl DULOXETINE HCL PELLETS N-METHYL DULOXETINE-NAPHTHYL-D7 (-)-2-[METHYLAMINO]-1-PHENYLPROPANE 5-Hydroxy-6-methoxy Duloxetine DULOXETINE MALEATE 4-Hydroxy Duloxetine -D-Glucuronide,4-Hydroxy Duloxetine b-D-Glucuronide Kresoxim-methyl Duloxetine-naphthyl-D7 Maleate Thiophanate-methyl Duloxetine-d3 HCl (rs)-duloxetine hydrochloride (R)-3-AMINO-1-(2-THIENYL)-1-PROPANOL 4-Hydroxy Duloxetine Duloxetine intermediate AA
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