4-HYDROXYPHENOXYACETIC ACID

4-HYDROXYPHENOXYACETIC ACID Basic information
Product Name:4-HYDROXYPHENOXYACETIC ACID
Synonyms:4-HYDROXYPHENOXYACETIC ACID;2-(4-Hydroxyphenoxy)acetic acid;2-(4-Hydroxyphenoxy)ethanoic acid, 4-(Carboxymethoxy)phenol;(P-HYDROXYPHENOXY)ACETIC ACID;(4-hydroxyphenoxy)-aceticaci;4-Hydroxyphenoxyacetic acid, 98+%;Acetic acid, 2-(4-hydroxyphenoxy)-;2-(4-hydroxyphenoxy)aceticaci
CAS:1878-84-8
MF:C8H8O4
MW:168.15
EINECS:217-525-8
Product Categories:Phenoxyacetic Acids and Alcohols (substituted);Carbonyl Compounds;Carboxylic Acids;C8
Mol File:1878-84-8.mol
4-HYDROXYPHENOXYACETIC ACID Structure
4-HYDROXYPHENOXYACETIC ACID Chemical Properties
Melting point 154-157 °C (lit.)
Boiling point 372.6±17.0 °C(Predicted)
density 1.367±0.06 g/cm3(Predicted)
solubility soluble in Methanol
pka3.27±0.10(Predicted)
form Fine Crystalline Powder
color Off-white to beige
BRN 1952779
LogP0.650
CAS DataBase Reference1878-84-8(CAS DataBase Reference)
EPA Substance Registry SystemAcetic acid, (4-hydroxyphenoxy)- (1878-84-8)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
TSCA Yes
HS Code 29189990
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
4-HYDROXYPHENOXYACETIC ACID Usage And Synthesis
Chemical Propertiesoff-white to beige fine crystalline powder
Uses2-(4-Hydroxyphenoxy)acetic Acid is used in the design, synthesis and evaluation of postulated transient intermediate and substrate analogues as inhibitors of 4-hyroxyphenylpyruvate dioxygenase. Acts as a reagent in the preparation, anti-HIV and kinesin Eg5 inhibitory activities, QSAR, and modeling studies of triazolothiadiazole and triazolothiadiazine derivatives. Synthesis of thiadiazolotriazin-4-ones and study of their mosquito-larvicidal and antibacterial properties.
DefinitionChEBI: 4-Hydroxypheoxyacetate is a monocarboxylic acid.
General Description(4-Hydroxyphenoxy)acetic acid along with formaldehyde ammonium salt forms a polyaromatic anionic compound RG-13577. RG-13577 mimics the synthetic heparin and specifically binds to the vascular smooth muscle cells (SMCs) and inhibits their proliferative growth. In the molecules of (4-hydroxyphenoxy)acetic acid, the carboxyl groups are held together by R22(8) hydrogen bonds.
4-HYDROXYPHENOXYACETIC ACID Preparation Products And Raw materials
Preparation Products2-(4-hydroxyphenoxy)acetamide-->Methyl 2-(4-hydroxyphenoxy)acetate
2-HYDROXYPHENOXYACETIC ACID,2-Hydroxyphenoxyacetic acid, 98+% DL-2-[4-(TRIFLUOROMETHOXY)PHENOXY]PROPIONIC ACID 2,4-Dichloro-5-hydroxyphenoxyacetic acid HYDROQUINONE-O,O'-DIACETIC ACID 2,5-dichloro-4-hydroxyphenoxyacetic acid 3-CHLORO-4-[2-(4-CHLOROPHENYL)HYDRAZONO]-2-(4-METHOXYPHENOXY)BUT-2-ENOIC ACID 3-CHLORO-2-(4-METHOXYPHENOXY)-4-[2-(4-NITROPHENYL)HYDRAZONO]BUT-2-ENOIC ACID DICLOFOP METHYL, 5-HYDROXY 3,5-DIBROMO-4-HYDROXYPHENOXYACETIC ACID Diclofop-methyl QUIZALOFOP 2-(4-HYDROXYPHENOXY)PROPIONIC ACID Quizalofop-p-ethyl 3-CHLORO-2-(4-METHOXYPHENOXY)-4-(2-PHENYLHYDRAZONO)BUT-2-ENOIC ACID 3-chloro-4-hydroxyphenoxyacetic acid o-Hydroxyphenoxyacetic acid 2-hydroxy-3-(o-tolyloxy)propyl ester 4-ACETOXYPHENOXYACETIC ACID Diclofop

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