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| | GALLEIN Basic information |
| | GALLEIN Chemical Properties |
| Melting point | >300°C | | Boiling point | 389.44°C (rough estimate) | | density | 1.2392 (rough estimate) | | refractive index | 1.6120 (estimate) | | storage temp. | Sealed in dry,Room Temperature | | solubility | Solubility Almost insoluble in water, benzene, chloroform; soluble in ethanol, acetone | | Colour Index | 45445 | | pka | 5.99(at 25℃) | | form | powder | | color | Brownish-red | | PH Range | Yellow (3.8) to rose-red (6.6);Pink (10.6) to violet (13.0) | | λmax | 526nm | | Merck | 14,4344 | | Stability: | Hygroscopic | | Major Application | Organic light emitting devices (OLED), treatment of cancer cells, diagnosis and treatment of amyloidosis, cancer chemo preventive activity, inhibition of influenza virus, semiconductors, photoresists, lithographic printing plates, method for ozone determination, treatment of wastewater, determination of silver, nail polish, monitoring sterilization, determination of proteins, induce apoptosis in cancer cells, treatement of cancer cells, antiHIV agent, cancer chemopreventive activity, drug design | | CAS DataBase Reference | 2103-64-2 | | EPA Substance Registry System | Gallein (2103-64-2) |
| | GALLEIN Usage And Synthesis |
| Uses | Gallein inhibits neutrophil chemotaxis and inflammation, via the disruption of G protein βγ subunit signaling. | | Definition | ChEBI: A xanthene dye that is fluoran carrying four hydroxy substituents at positions 3', 4', 5' and 6'. | | Preparation | 3,4,5-Trihydroxybenzoic acid or Benzene-1,2,3-triol?and Phthalic anhydride?in 190 ~ 200 ℃ reaction (namely GALLEIN), and then into sodium salt namely Alizarine Violet. | | Biological Activity | Inhibitor of G protein β γ subunit-dependent signaling. Blocks PI 3-kinase and Rac1 activation in HL60 cells and chemotaxis in HL60 differentiated cells. | | storage | Store at -20°C | | Properties and Applications | blue light purple. Free acid soluble in hot water for the big red, soluble in hot ethanol for red light brown. In concentrated sulfuric acid to red light yellow, after dilution with fluorescence red yellow precipitation. Dye aqueous solution to join sodium hydroxide as blue.
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Standard
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Ironing Fastness
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Light Fastness
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Fulling
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Persperation Fastness
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Soaping
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Water
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Alkali
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Acid
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ISO
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4-5
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4
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4
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5
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4
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5
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AATCC
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5
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4-5
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5
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5
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5
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| | GALLEIN Preparation Products And Raw materials |
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