2-QUINOXALINECARBONYL CHLORIDE

2-QUINOXALINECARBONYL CHLORIDE Basic information

Product Name:	2-QUINOXALINECARBONYL CHLORIDE
Synonyms:	2-QUINOXALOYL CHLORIDE;2-QUINOXALINECARBONYL CHLORIDE;TIMTEC-BB SBB000309;quinoxaline-2-carbonyl chloride;2-Quinoxalinecarbonyl chloride (7CI, 9CI);2-Quinoxaloyl chloride,97+%;2-(Chlorocarbonyl)quinoxaline, 1,4-Benzodiazine-2-carbonyl chloride;2-Quinoxoyl chloride
CAS:	54745-92-5
MF:	C9H5ClN2O
MW:	192.6
EINECS:	259-315-9
Product Categories:	ACIDHALIDE
Mol File:	54745-92-5.mol

2-QUINOXALINECARBONYL CHLORIDE Chemical Properties

Melting point	113-115 °C (lit.)
storage temp.	2-8°C
form	Liquid
color	Clear colorless to pale yellow
CAS DataBase Reference	54745-92-5

Safety Information

MSDS Information

Provider	Language
ACROS	English
SigmaAldrich	English

2-QUINOXALINECARBONYL CHLORIDE Usage And Synthesis

Chemical Properties	Off-white to tan crystalline powder
Uses	Reactant involved in the synthesis of a variety of inhibitors including: Gelatinase inhibitors for cancer treatments mGluR5 non-competitve antagonists Heterocyclic analogs used as SIRT1 activators 3rd Generation multidrug resistance modulators Reactant involved in preparation of PET ligants for breast cancer resistance protein imaging
General Description	2-Quinoxaloyl chloride reacts with chiral α-hydroxy carboxylic acids to yield UV and fluorescent derivatives.

2-QUINOXALINECARBONYL CHLORIDE Preparation Products And Raw materials

Raw materials	Ethanol-->Hydrochloric acid-->Ethyl acetate-->Thionyl chloride-->PETROLEUM ETHER-->Toluene-->Sulfuryl chloride-->Oxalyl chloride-->o-Phenylenediamine-->Potassium dichromate-->Carbon-->2-Methylquinoxaline-->SODIUM DIHYDROXYTARTRATE
Preparation Products	N-[2-[3-(1-Piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl]phenyl]-2-quinoxalinecarboxamide-->4-[[6-[2-[(2-QUINOXALINYLCARBONYL)AMINO]PHENYL]IMIDAZO [2,1-B]THIAZOL-3-YL]METHYL]-1-PIPERAZINECARBOXYLIC ACID 1,1-DIMETHYLETHYL ESTER

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