5-Chlorooxindole

5-Chlorooxindole Basic information
Product Name:5-Chlorooxindole
Synonyms:4-chloroindole-2(3h)-one;5-Chloroindole-2(3H)-one;5-CHLOROINDOLIN-2-ONE 5-CHLOROOXINDOLE 5-CHLORO-1,3-DIHYDROINDOLE-2-ONE;5-CHLOROINDOLE-2-ONE;3-dihydroindole-2-one;5-Chlorooxindole ,99%;5-CHLOROOXINDOLE, 97+%;5-Chloro-1H-indol-2(3H)-one
CAS:17630-75-0
MF:C8H6ClNO
MW:167.59
EINECS:412-200-9
Product Categories:blocks;IndolesOxindoles;Indole/indoline/oxindole;Indole and Indoline;Indoles and derivatives;Indole;Indoles;oxindoles;Heterocycles
Mol File:17630-75-0.mol
5-Chlorooxindole Structure
5-Chlorooxindole Chemical Properties
Melting point 194-197 °C (lit.)
Boiling point 348.3±42.0 °C(Predicted)
density 1.362±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility Slightly Soluble (2.0 g/L) (25°C).
pka13.14±0.20(Predicted)
form Solid
color Light Orange to Brown
InChIKeyWWJLCYHYLZZXBE-UHFFFAOYSA-N
CAS DataBase Reference17630-75-0(CAS DataBase Reference)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 22-43-52/53-62-36/37/38
Safety Statements 22-36/37-61-45-36/37/39-24-37/39-26
WGK Germany 2
Hazard Note Irritant/Keep Cold
HS Code 29339900
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
5-Chlorooxindole Usage And Synthesis
Chemical PropertiesTan powder
Uses5-Chloro-2-oxindole was used for the quantitation of 5-chloro-2-oxindole, concomitantly with all of its potential positional isomers using a single, highly specific, normal-phase chromatographic system. 5-Chloro-2-oxindole (5-Chlorooxindole) is a starting material for tenidap sodium, a pharmaceutical drug candidate.
Uses5-Chlorooxindole is used in the preparation of novel GSK-3β inhibitors as anticancer agents.
Synthesis Reference(s)Journal of Heterocyclic Chemistry, 25, p. 1279, 1988 DOI: 10.1002/jhet.5570250501
General Description5-Chloro-2-oxindole (5-Chlorooxindole) is a starting material for tenidap sodium, a pharmaceutical drug candidate.
5-Chloroisatin 5-CHLORO-1-(3,4-DICHLOROBENZYL)-3-[(PENTANOYLOXY)IMINO]-1,3-DIHYDRO-2H-INDOL-2-ONE 5-CHLORO-1-(4-CHLOROBENZYL)-1H-INDOLE-2,3-DIONE 3-OXIME 5-CHLORO-1-[3-(TRIFLUOROMETHYL)BENZYL]-1H-INDOLE-2,3-DIONE 5-CHLORO-3-([(2-CHLOROACETYL)OXY]IMINO)-1-(3,4-DICHLOROBENZYL)-1,3-DIHYDRO-2H-INDOL-2-ONE 4,5,7-trichloro-1H-indole-2,3-dione 5-CHLOROACETYL-6-CHLOROOXINDOLE,5-cloroacetyl-6-chlorooxindole 1-(2,6-Dichlorophenyl)indolin-2-one 5-CHLORO-1-(4-CHLOROBENZYL)-1H-INDOLE-2,3-DIONE Oxindole 5,7-Dichloro-1H-indole-2,3-dione 5-CHLORO-1-(3,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE 3-OXIME 5-CHLORO-1-(3,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE cis-Octahydro-isoindole 3-[(ACETYLOXY)IMINO]-5-CHLORO-1-(3,4-DICHLOROBENZYL)-1,3-DIHYDRO-2H-INDOL-2-ONE 3,3'-Diindolylmethane 5-CHLORO-1-(3,4-DICHLOROBENZYL)-3-([(3-METHYLBUTANOYL)OXY]IMINO)-1,3-DIHYDRO-2H-INDOL-2-ONE 5-CHLORO-7-METHYLISATIN

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