3-Anilino-2-(3,4,5-triMethoxybenzyl)acrylonitrile, (Mixture of cis/trans isoMers)

3-Anilino-2-(3,4,5-triMethoxybenzyl)acrylonitrile, (Mixture of cis/trans isoMers) Basic information
Product Name:3-Anilino-2-(3,4,5-triMethoxybenzyl)acrylonitrile, (Mixture of cis/trans isoMers)
Synonyms:Trimethoprim Impurity 9 (Trimethoprim EP Impurity I);3-ANILINO-2-(3,4,5-TRIMETHOXYBENZYL) ACRYLONITRILE (25 MG) (AS);(Z)-3-anilino-2-[(3,4,5-trimethoxyphenyl)methyl]prop-2-enenitrile;Trimethoprim EP Impurity I;3,4,5-Trimethoxy-α-[(phenylamino)methylene]benzenepropiononitrile;3-Anilino-2-(3,4,5-Trimethoxybenzyl)acrylonitrile, Mixture of double bond isomers;3-(Phenylamino)-2-(3,4,5-trimethoxybenzyl)acrylonitrile;3-Anilino-2-(3,4,5-trimethoxybenzyl)acrylonitrile, Trimethoprim Impurity I
CAS:30078-48-9
MF:C19H20N2O3
MW:324.37
EINECS:250-033-1
Product Categories:Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:30078-48-9.mol
3-Anilino-2-(3,4,5-triMethoxybenzyl)acrylonitrile, (Mixture of cis/trans isoMers) Structure
3-Anilino-2-(3,4,5-triMethoxybenzyl)acrylonitrile, (Mixture of cis/trans isoMers) Chemical Properties
Melting point 130-136°C
Boiling point 500.2±50.0 °C(Predicted)
density 1.167±0.06 g/cm3(Predicted)
storage temp. Refrigerator
solubility Chloroform, Methanol
pka-0.83±0.70(Predicted)
form Solid
color White to Off-White
CAS DataBase Reference30078-48-9
Safety Information
HS Code 2926907090
MSDS Information
3-Anilino-2-(3,4,5-triMethoxybenzyl)acrylonitrile, (Mixture of cis/trans isoMers) Usage And Synthesis
Chemical PropertiesWhite Crystalline Solid
Uses3-Anilino-2-(3,4,5-triMethoxybenzyl)acrylonitrile, (Mixture of cis/trans isoMers)is used as a reference standard for the drug Trimethoprim. Note this compound is a cis/trans mixture.
3-Anilino-2-(3,4,5-triMethoxybenzyl)acrylonitrile, (Mixture of cis/trans isoMers) Preparation Products And Raw materials
Preparation ProductsTrimethoprim
2,3,4-TRIMETHOXYPHENYLACETIC ACID TriMethopriM IMpurity C 3-Iodobenzyl bromide 2,3,4-Trihydroxybenzaldehyde Trimethoprim Related Compound B (25 mg) (2,4-diaminopyrimidin-5-yl)(3,4,5-trimethoxyphenyl)methanone) (AS) 1,4-Bis(2,3,4-triMethoxybenzyl)piperazine 4-[(2,3,4-TriMethoxyphenyl)Methyl]-1-piperazinecarboxylic Acid Ethyl Ester 1-Dimethylamino-2-phenylbutan-2-yl 3,4,5-trimethoxybenzoate Cefaclor 4-ALLYL-2,6-DIMETHOXYPHENOL 3-(3,5-DIMETHOXYPHENYL)-2-METHYL-1-PROPENE 3-Anilino-2-(3,4,5-triMethoxybenzyl)acrylonitrile, (Mixture of cis/trans isoMers) Trimethoprim Elemicin 3-(3,4-DIMETHOXYPHENYL)-2-METHYL-1-PROPENE 3-(3,5-DIMETHOXYPHENYL)-1-PROPENE AURORA 13948 3-(4-METHOXYPHENYL)PROPIONITRILE

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