Rivaroxaban Impurity 61

Rivaroxaban Impurity 61 Basic information
Product Name:Rivaroxaban Impurity 61
Synonyms:Rivaroxaban impurity O: M1 + 2M2;2,2'-[[[4-(3-Oxo-4-morpholinyl)phenyl]imino]bis[(2R)-2-hydroxy-3,1-propanediyl]]bis[1H-isoindole-1,3(2H)-dione];1H-Isoindole-1,3(2H)-dione, 2,2'-[[[4-(3-oxo-4-morpholinyl)phenyl]imino]bis[(2R)-2-hydroxy-3,1-propanediyl]]bis-;2,2'-((2R,2'R)-((4-(3-oxomorpholino)phenyl)azanediyl)bis(2-hydroxypropane-3,1-diyl))bis(isoindoline-1,3-dione);Rivaroxaban Impurity 75 (Rivaroxaban Impurity)
CAS:1643354-27-1
MF:C32H30N4O8
MW:598.6
EINECS:
Product Categories:
Mol File:1643354-27-1.mol
Rivaroxaban Impurity 61 Structure
Rivaroxaban Impurity 61 Chemical Properties
Melting point 182-184°C
Boiling point 904.3±65.0 °C(Predicted)
density 1.473±0.06 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
pka13.55±0.20(Predicted)
form Solid
color Off-White to Light Yellow
Stability:Hygroscopic
Safety Information
MSDS Information
Rivaroxaban Impurity 61 Usage And Synthesis
Uses2,?2''-?[[[4-?(3-?Oxo-?4-?morpholinyl)?phenyl]?imino]?bis[(2R)?-?2-?hydroxy-?3,?1-?propanediyl]?]?bis[1H-?isoindole-?1,?3(2H)?-?dione] is an impurity of Rivaroxaban (R538000), a novel antithrombotic agent. A highly potent and selective, direct FXa inhibitor.
Rivaroxaban Impurity 61 Preparation Products And Raw materials
2-ThiophenecarboxaMide, 5-chloro-N,N-diMethyl- Rivaroxaban Impurity 43 (R)-5-chloro-N-(4-(3-oxomorpholino)phenyl)-N- ((2-oxooxazolidin-5-yl)methyl)thiophene-2-carboxamide Rivaroxaban Impurity 79 2-ThiophenecarboxaMide, N-[[(5S)-2-oxo-3-[4-(3-oxo-4-Morpholinyl)phenyl]-5-oxazolidinyl]Methyl]- AcetaMide, N-[[(5S)-2-oxo-3-[4-(3-oxo-4-Morpholinyl)phenyl]-5-oxazolidinyl]Methyl]- 4,5-dichloro Rivaroxaban Rivaroxaban Impurity 12 (S)-2-(3-chloro-2-hydroxypropyl)isoindoline-1,3-dione Rivaroxaban Impurity 55 (S)-5-chloro-N-(3-(5-chlorothiophene-2-carboxamido)-2- hydroxypropyl)-N-(4-(3-oxomorpholino)phenyl)thiophene-2- carboxamide (S)-methyl((2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl) methyl)carbamate Rivaroxaban Impurity 88 Rivaroxaban Impurity 31 Rivaroxaban Impurity 41 2-ThiophenecarboxaMide, 5-chloro-N-[(2S)-2-hydroxy-3-[[4-(3-oxo-4-Morpholinyl)phenyl]aMino]propyl]- Benzoic acid, 2-[[[[(5S)-2-oxo-3-[4-(3-oxo-4-Morpholinyl)phenyl]-5-oxazolidinyl]Methyl]aMino]carbonyl]- 4-(3-nitrophenyl)-3-Morpholinone

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