Ancymidol

Ancymidol Basic information
Product Name:Ancymidol
Synonyms:α-cyclopropyl-α-(4-methoxyphenyl)-5-pyrimidinemethanol;ALPHA-CYCLOPROPYL-A(P-METHOXYPHENYL)-5-PYRIMIDINE METHANOL;ancymidol (bsi,e-iso,ansi);ancymidole ((m)f-iso);5-PYRIMIDINEMETHANOL,ALPHA-CYCLOPROPYL-ALPHA-(PARA-METHOXYPHENYL);a-Cyclopropyl-a-(4-methoxyphenyl)-5-pyrimidinemethanol;a-Cyclopropyl-a-(methoxyphenyl)-5-pyrimidinemethanol;Thritone
CAS:12771-68-5
MF:C15H16N2O2
MW:256.3
EINECS:235-814-7
Product Categories:plantgrowth
Mol File:12771-68-5.mol
Ancymidol Structure
Ancymidol Chemical Properties
Melting point 110-111°C
Boiling point 399.55°C (rough estimate)
density 1.1055 (rough estimate)
refractive index 1.6280 (estimate)
storage temp. 2-8°C
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
pka12.62±0.29(Predicted)
color White to Off-White
Water Solubility 0.65g/L(25 ºC)
λmax272nm(lit.)
CAS DataBase Reference12771-68-5(CAS DataBase Reference)
NIST Chemistry ReferenceAncymidol(12771-68-5)
EPA Substance Registry SystemAncymidol (12771-68-5)
Safety Information
Safety Statements 22-24/25
WGK Germany 3
RTECS UV9280000
HS Code 2933599590
ToxicityLD50 in rats, mice (mg/kg): 4500, 5000 orally (Snel, Gramlich)
MSDS Information
ProviderLanguage
Ancymidol English
SigmaAldrich English
Ancymidol Usage And Synthesis
Chemical PropertiesAncymidol is a white to buff colored crystalline or granular solid. Slightly aromatic odor.
UsesPlant growth regulator.
UsesAncymidol has been used as the cytochrome P450 inhibitor to study its effects on Cyanidioschyzon merolae?strain.
DefinitionChEBI: A tertiary alcohol that is methanol in which the hydrogens attached to the carbon are replaced by cyclopropyl, p-methoxyphenyl and pyrimidin-5-yl groups. By inhibiting gibberellin biosynthesis, ancymidol reduces plant growth, resulting in redu ed internode elongation and thus more compact plants. It is used in the commercial production of a wide variety of container-grown bedding and foliage plants, including chrysanthemums, Easter lilies and poinsettias.
General DescriptionAncymidol, a-cyclopropyl-a-(4-methoxyphenyl)-5-pyrimidinemethanol (EL-53 1), a plant growth retardant is a synthetic pyrimidine analogue. It is also a weak fungitoxic.
Biochem/physiol ActionsAncymidol is a pyrimidine-class plant cell endocrine disruptor plant growth regulator that interferes with gibberellin and cellulose biosynthesis.
Potential ExposureAncymidol is a plant growth regulator registered for treating container-grown herbaceous plants, ornamental woody shrubs, and bedding plants grown in greenhouses and other plant bedding areas for primarily commercial production. Growth regulator used on plants such as chrysanthemums, certain lilies, and poinsettias effects produced by ancymidol are the result of inhibition of gibberellin biosynthesis. It produces a more compact growth form by suppressing elongation.
IncompatibilitiesDust may form explosive mixture with air. Ancymidol may react vigorously with oxidizing agents. Mixtures with concentrated hydrogen peroxide or strong mineral acids (e.g., nitric, sulfuric, perchloric) may cause explosions. Mixtures with hypochlorous acid, lead perchlorate, chlorine, bleaches, including sodium hypochlorite; mixed water/carbon tetrachloride solution; trichloroisocyanuric acid form methyl hypochlorite, which can be explosive, especially when exposed to sunlight or heat. May react with metallic aluminum at high temperature. Flow or agitation of substance may generate electrostatic charges due to low conductivity; ground all equipment containing this material. May attacks some plastics, rubber, and coatings.
Waste DisposalDispose of contents and container to an approved waste disposal plant. All federal, state, and local environmental regulations must be observed. References
Ancymidol Preparation Products And Raw materials
Preparation ProductsEAM resin adhesive modified with diisocyanate for orthodontias-->Diazinon-->2-METHOXY-6-METHYL-4(1H)-PYRIMIDINONE
ALPHA-CYCLOPROPYLBENZYL ALCOHOL Ancymidol 4-Methoxybenzyl alcohol ANCYMIDOL SOLUTION 100UG/ML IN METHANOL 1ML 1-CYCLOPROPYL-1-PHENYLETHANOL 2-Nitrobenzyl alcohol 1-CYCLOPROPYLETHANOL 4-Hydroxybenzyl alcohol Propargyl alcohol 1-(4-METHYOXYPHENYL)-1-PROPANOL 97 Cyproconazol 1-CYCLOPROPYL-1-METHYLETHANOL Pyrimidine ALPHA-NAPHTHOLBENZEIN Allylestrenol 1,1-Bis(hydroxymethyl)cyclopropane Fenarimol Diethylstilbestrol

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