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THIOTHIAMINE

THIOTHIAMINE Basic information
Product Name:THIOTHIAMINE
Synonyms:3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-2(3H)-Thiazolethione;sulbone;3-(4-Amino-2-methyl-5-pyrimidinylmethyl)-5-(2-hydroxyethyl)-4-methyl-4-thiazoline-2-thione;3-[(2-Methyl-4-amino-5-pyrimidinyl)methyl]-5-(β-hydroxyethyl)-4-methyl-4-thiazoline-2-thione;Solbone;Thiothlamine;Thiamin-2-thione;Thiamin EP Impurity E
CAS:299-35-4
MF:C12H16N4OS2
MW:296.41
EINECS:206-077-9
Product Categories:Impurities;Aromatics;Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Neurochemicals;Pharmaceuticals;Sulfur & Selenium Compounds
Mol File:299-35-4.mol
THIOTHIAMINE Structure
THIOTHIAMINE Chemical Properties
Melting point 238-239 °C
Boiling point 509.6±60.0 °C(Predicted)
density 1.42±0.1 g/cm3(Predicted)
storage temp. Refrigerator
solubility DMSO (Slightly), Methanol (Very Slightly, Heated)
pka14.72±0.10(Predicted)
form Solid
color Pale Beige to Light Brown
Safety Information
MSDS Information
THIOTHIAMINE Usage And Synthesis
UsesThiothiamine is an impurity of Thiamine (T344185). Thiothiamine inhibits the activity of glutamate decarboxylase and decreases the concentration of GABA in brain tissue. Thiamine Impurity A;
THIOTHIAMINE Preparation Products And Raw materials
Preparation ProductsTHIAMINE HYDROCHLORIDE
3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methylthiazol-2(3H)-one Thiamine 4-AMino-5-(forMaMidoMethyl)-2-MethylpyriMidine ThiaMine Acetate 3-[(4-AMino-2-Methyl-5-pyriMidinyl)Methyl]-4-Methyl-5-[2-(sulfooxy)ethyl]thiazoliuM Inner Salt Cyclohexanone,2-amino-2-(2-chlorophenyl)-6-hydroxy-,(2R-cis)-(9Cl) (R)-Norketamine 1-[2-(acetoxy)ethyl]-2-oxopropyl [(4-amino-2-methyl-5-pyrimidinyl)methyl]dithiocarbamate FWNAAOBWGCASMX-UHFFFAOYSA-M Thiamine Impurity 27 Thiamine Impurity 22 Beclotiamine Hydrochloride Thiamine hydrochloride THIOTHIAMINE 4-Methylthiazole 3,4-Dimethyl-4-thiazoline-2-thione 5-(2-Hydroxyethyl)-4-methylthiazole 2-HYDROXYETHYL N-PENTYL SULPHIDE, 95
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