8-Hydroxyquinoline-5-sulfonic acid

8-Hydroxyquinoline-5-sulfonic acid Basic information
Product Name:8-Hydroxyquinoline-5-sulfonic acid
Synonyms:5-Sulfo-8-hydroxyquinoline;5-Sulfo-8-quinolinol;5-Sulfooxine;8-hydroxy-5-quinolinesulfonicaci;8-Hydroxy-5-sulfoquinoline;8-Hydroxyquinoline-5-sulfonate;8-Hydroxyquinoline-5-sulfonic;8-Hydroxyquinoline-5-sulphonic acid
CAS:84-88-8
MF:C9H7NO4S
MW:225.22
EINECS:201-570-5
Product Categories:Building Blocks;C8 to C10;Building Blocks;Heterocyclic Building Blocks;Chemical Synthesis;Heterocyclic Building Blocks;Quinoline series;Organic acids;Hydroxyquinolines;Quinolines
Mol File:84-88-8.mol
8-Hydroxyquinoline-5-sulfonic acid Structure
8-Hydroxyquinoline-5-sulfonic acid Chemical Properties
Melting point 311-313°C
density 1.4899 (rough estimate)
refractive index 1.5364 (estimate)
storage temp. Inert atmosphere,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
form crystalline
pkapK1:4.092(+1);pK2:8.776(0) (25°C)
color yellow to green
Merck 4844
Stability:Hygroscopic
CAS DataBase Reference84-88-8(CAS DataBase Reference)
NIST Chemistry Reference5-Quinolinesulfonic acid, 8-hydroxy-(84-88-8)
EPA Substance Registry System5-Quinolinesulfonic acid, 8-hydroxy- (84-88-8)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 22-36-36/37/38
Safety Statements 26-36
RIDADR 2811
WGK Germany 3
RTECS VC2570000
HazardClass 6.1(b)
PackingGroup III
HS Code 29334990
MSDS Information
ProviderLanguage
8-Hydroxyquinoline-5-sulfonic acid English
SigmaAldrich English
8-Hydroxyquinoline-5-sulfonic acid Usage And Synthesis
Chemical PropertiesYellow fine crystalline powder
Uses8-Hydroxy-5-quinolinesulfonic acid is used in the synthesis of fat mass and obesity associated proteins. Also used in the synthesis of anti-schitosomal compounds.
Purification MethodsCrystallise the acid from water (as the 1.5 hydrate, m 316-317o) or dilute HCl (ca 2% by weight). [Beilstein 22 I 620, 22 II 313, 22 III/IV 3493.]
8-Hydroxyquinoline-5-sulfonic acid Preparation Products And Raw materials
Raw materialsFUMING SULFURIC ACID-->8-Hydroxyquinoline
8-hydroxyquinoline-5,7-disulphonic acid 8-Hydroxyquinoline-5-sulfonic acid p-Toluenesulfonic acid Ethyl 2-(Chlorosulfonyl)acetate Taurine Ascoric Acid 8-ETHOXYQUINOLINE-5-SULFONIC ACID SULFONIC ACID Folic acid quinobene 1-DODECANESULFONIC ACID SODIUM SALT 7-(6-SULFO-2-NAPHTHYLAZO)-8-HYDROXYQUINOLINE-5-SULFONIC ACID SODIUM SALT Sulfamic acid 7-IODO-8-HYDROXYQUINOLINE-5-SULFONIC ACID NAPHTHYLAZOXINE 8-Hydroxyquinoline Quinhydrone 8-HYDROXYQUINOLINE-5-SULFONIC ACID N-HYDRATE,8-HYDROXYQUINOLINE-5-SULFONIC ACID MONOHYDRATE,8-HYDROXYQUINOLINE-5-SULFONIC ACID MONOHYROATE

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