3'-Hydroxyacetophenone

3'-Hydroxyacetophenone Basic information
Product Name:3'-Hydroxyacetophenone
Synonyms:m-Hydroxyacetophenonel;3'-Hydroxyacetophenone 3-Acetylphenol m-Acetylphenol;3'-HYDROXYACETOPHENONE, 99+%;3-Hydroxyacetophenone98%;1-(3-Hydroxyphenyl)ethan-1-one, 3-Acetylphenol;3-Acetophenol 3-Acetylphenol 3-Hydroxyphenyl Methyl Ketone;1-(3-hydro;Etilefrine Impurity E (3-Hydroxy Acetopheone)
CAS:121-71-1
MF:C8H8O2
MW:136.15
EINECS:204-494-0
Product Categories:C7 to C8;Ketones;Organic Photoinitiators;Polymerization Initiators;Building Blocks;C7 to C8;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks;Drug, phenylephrine intermediates;Aromatic Acetophenones & Derivatives (substituted);Carbonyl Compounds;AcetophenoneCarbonyl Compounds;Chemical;121-71-1
Mol File:121-71-1.mol
3'-Hydroxyacetophenone Structure
3'-Hydroxyacetophenone Chemical Properties
Melting point 90-95 °C(lit.)
Boiling point 296 °C(lit.)
density 1.1 g/mL at 25 °C(lit.)
vapor pressure 0.022Pa at 25℃
refractive index 1,534
Fp 296°C
storage temp. Inert atmosphere,Room Temperature
solubility 22g/l
form Crystalline Powder
pka9.19(at 25℃)
color Beige-brown
Water Solubility Soluble in alcohol. Insoluble in water.
BRN 2040676
InChIKeyLUJMEECXHPYQOF-UHFFFAOYSA-N
LogP1.144 at 25℃
CAS DataBase Reference121-71-1(CAS DataBase Reference)
NIST Chemistry ReferenceEthanone, 1-(3-hydroxyphenyl)-(121-71-1)
EPA Substance Registry SystemEthanone, 1-(3-hydroxyphenyl)- (121-71-1)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 22-36/37/38
Safety Statements 22-24/25-37/39-26-36
WGK Germany 3
Hazard Note Harmful/Irritant
TSCA Yes
HS Code 29143990
MSDS Information
ProviderLanguage
m-Hydroxyacetophenone English
SigmaAldrich English
ACROS English
ALFA English
3'-Hydroxyacetophenone Usage And Synthesis
Description3’-Hydroxyacetophenone is a chemical compound and it is a component of castoreum, the exudate from the castor sacs of the mature beaver. It is used in the synthesis and preparation of chalcones and flavonoids as anti-tuberculosis agents, as well as antileishmanial chaocones.
Chemical Propertiesbeige-brown crystalline powder
Uses3’Hydroxyacetophenone is a chemical reagent used in the synthesis and preparation of chalcones and flavonoids as anti-tuberculosis agents, as well as antileishmanial chaocones.
Uses3?Hydroxyacetophenone is used in the preparation of chalcones and flavonoids, which finds application as an anti-tuberculosis agent and antileishmanial chaocones. It is also involved in the preparation of phenylephrine. Further, it is an active component of castoreum, which is used as a tincture in some perfumes and as a food additive.
UsesUseful in the preparation of chalcones, flavonoids, and phenylephrine. It is an active component of castoreum, which is used as a tincture in some perfumes and as a food additive.
PreparationPreparation by diazotization of 3-aminoacetophenone, followed by hydrolysis of the obtained diazonium salt (78–82%).
General Description3′-Hydroxyacetophenone is an hydroxy-substituted alkyl phenyl ketone.
Flammability and ExplosibilityNonflammable
2',3'-DIHYDROXYACETOPHENONE PARACETAMOL IMP. I (EP): 1-(2-HYDROXYPHENYL)ETHANONE(2-HYDROXYACETOPHENONE) 4-BENZYLOXY-3-HYDROXYACETOPHENONE 2',4',6'-Trihydroxyacetophenone monohydrate 5-Bromo-3-Nitro-2-Hydroxyacetophenone 5'-Bromo-3'-Nitro-2'-Hydroxyacetophenone 4-Methyl-2-Hydroxyacetophenone PARACETAMOL IMP. G (EP): 1-(4-HYDROXYPHENYL)ETHANONEOXIME (4-HYDROXYACETOPHENONE OXIME) w-Bromo-4-Hydroxyacetophenone 1-(3-CHLOROMETHYL-4-HYDROXY-PHENYL)-ETHANONE 3' 5'-DIBROMO-2'-HYDROXYACETOPHENONE 9&,-hydroxyacetophenone 2-(2-CHLOROPHENYL)-5'-FLUORO-2'-HYDROXYACETOPHENONE 3,4-Dihydroxyacetophenone 3',5'-DICHLORO-2'-HYDROXYACETOPHENONE, 9 9% 5-ACETAMIDO-2-HYDROXYACETOPHENONE MM(CRM STANDARD) PARACETAMOL IMP. I (EP): 2-HYDROXYACETOPHENONE MM(CRM STANDARD) 3'-BROMO-4'-HYDROXYACETOPHENONE 2-Bromo-4-Hydroxyacetophenone98% 2-Acetyl-4-butyramidophenol

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