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4-Epoxypropanoxycarbazole

4-Epoxypropanoxycarbazole Basic information
Product Name:4-Epoxypropanoxycarbazole
Synonyms:Carvedilol Related Compound D (USP);4-EPOXYPROPANOXYCARBAZOLE;Carvedilol Epoxide Impurity;4-(2-Oxiranylmethyoxy)-9H-carbazole;4-OXIRANYLMETHOXY-9H-CARBAZOLE;4-GLYCIDYLOXYCARBAZOLE;4-(2-OXIRANYLMETHOXY)-9H-CARBAZOLE;4-(2,3-EPOXYPROPOXY)CARBAZOLE
CAS:51997-51-4
MF:C15H13NO2
MW:239.27
EINECS:610-764-2
Product Categories:Impurities;pharma material;Aromatics;Aromatics Compounds;Carbazoles;Oxiranes;Simple 3-Membered Ring Compounds;Carvedilol Intermediate;(intermediate of carvedilol);Chemical intermediate for Benidipin;PHARMACEUTICAL INTERMEDIATES
Mol File:51997-51-4.mol
4-Epoxypropanoxycarbazole Structure
4-Epoxypropanoxycarbazole Chemical Properties
Melting point 130-132°C
Boiling point 464.9±15.0 °C(Predicted)
density 1.327±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
pka16.59±0.30(Predicted)
form neat
color Off-White to Light Brown
BRN 918742
InChIKeySVWKIGRDISDRLO-UHFFFAOYSA-N
CAS DataBase Reference51997-51-4(CAS DataBase Reference)
Safety Information
Hazard Codes Xi,Xn
Risk Statements 43-68
Safety Statements 36/37
WGK Germany 3
HazardClass IRRITANT
HS Code 29339900
MSDS Information
4-Epoxypropanoxycarbazole Usage And Synthesis
Chemical PropertiesPale Yellow to Almost White Powder
Uses4-(2,3-Epoxypropoxy)carbazole (Carvedilol EP Impurity D; Carvedilol USP-D) is an intermediate in the synthesis of Carvedilol (C184625).
(S)-(-)-CARVEDILOL Carvedilol Bisalkylpyrocatechol IMpurity 6,7,8,9-Tetrahydro Carvedilol 4-(oxiranylmethoxy)-1H-indole (R)-(-)-4-(2,3-EPOXYPROPOXY)CARBAZOLE 4-Epoxypropanoxycarbazole Hexafluoropropylene oxide (S)-(+)-4-(2,3-EPOXYPROPOXY)CARBAZOLE Carbazole Epichlorohydrin 4-Hydroxy carbazole Propylene oxide
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