5-METHYLCYTIDINE

5-METHYLCYTIDINE Basic information
Product Name:5-METHYLCYTIDINE
Synonyms:5-METHYLCYTIDINE;5-METHYLCYTIDINE, 98.0+%(LC)(T);Cytidine, 5-Methyl-;3: PN: US20060035254 PAGE: 63 claimed sequence;NSC 363933;4-amino-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-pyrimidin-2-one;4-aMino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-5-MethylpyriMidin-2(1H)-one;5-Me-Cr
CAS:2140-61-6
MF:C10H15N3O5
MW:257.24
EINECS:218-390-8
Product Categories:Biochemistry;Nucleosides and their analogs;Nucleosides, Nucleotides & Related Reagents;Biochemicals and Reagents;Nucleoside Analogs;Nucleosides, Nucleotides, Oligonucleotides
Mol File:2140-61-6.mol
5-METHYLCYTIDINE Structure
5-METHYLCYTIDINE Chemical Properties
Melting point 212-215 °C (dec.) (lit.)
Boiling point 537.5±60.0 °C(Predicted)
density 1.79
refractive index 15 ° (C=2, H2O)
storage temp. Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility DMSO (Slightly), Methanol (Slightly), Water (Sparingly)
pkapK1:4.21 (25°C)
form Solid
color Off-White to Pale Beige
Stability:Hygroscopic
InChIKeyZAYHVCMSTBRABG-JXOAFFINSA-N
CAS DataBase Reference2140-61-6(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-24/25
WGK Germany 3
HS Code 29389090
MSDS Information
ProviderLanguage
SigmaAldrich English
5-METHYLCYTIDINE Usage And Synthesis
Chemical PropertiesWhite powder
Uses5-Methylcytidine is a derivative of Cytidine (C998300), found in ribonucleic acids of animals, plants and bacteria. 5-Methylcytidine is a nucleoside found in liver emulsion that can inhibit the growth of spontaneous tumors of mammary gland origin in mice. 5-Methylcytidine is one of many nucleosides that can be used as biomedical marker using liquid chromatography and ion trap mass spectrometry coupling.
Uses5-Methylcytidine is used in studies of DNA methylation processes (epigenetics).
DefinitionChEBI: 5-methylcytidine is a methylcytidine.
General Description5-Methylcytidine is a component of RNA in Escherichia coli. It is present in the RNA of plant, animal and bacterial origin. It is one of the C derivative present in transfer RNA (tRNA).
Biochem/physiol Actions5-Methylcytidine is an alkylated pyrimidine plays an important role enhancing the stacking in A- and B- helices of nucleic acid, results in increase of the melting temperature and improves thermal stability leading to structural stabilization.
5-METHYLCYTIDINE Preparation Products And Raw materials
Preparation Products5-METHYLCYTOSINE
TEXAS RED-5-CTP 5-(1-PROPYNYL)-2'-O-METHYLCYTIDINE LISSAMINE-5-CTP 2'-O-MOE-5-METHYLCYTIDINE TETRAMETHYLRHODAMINE-6-CTP 1-(3,5-DI-O-ACETYL-BETA-D-RIBOFURANOSYL)-4-(1,2,4-TRIAZOL-L-YL)-5-METHYLPYRMIDIN-2-ONE 5'-DMT, 2'-MOE-4-(1-METHYL-PYRROLIDIN)-5-METHYLCYTIDINE 5-AMINOALLYLCYTIDINE-5'-TRIPHOSPHATE LITHIUM SALT 2'-(O-METHYL)-5-METHYLCYTIDINE,5-METHYL-2'-O-METHYLCYTIDINE 5-METHYLCYTIDINE-5'-TRIPHOSPHATE LITHIUM SALT BIOTIN-11-CTP COUMARIN-5-CTP FLUORESCEIN-12-CTP 3'-(O-METHYL)-5-METHYLCYTIDINE NAPHTHOFLUORESCEIN-5-CTP FLUORESCEIN CHLOROTRIAZINYL-4-CTP 5-PROPYNYLCYTIDINE N4-BENZOYL-5'-O-(DIMETHOXYTRITYL)-5-METHYL-2'-O-METHYLCYTIDINE

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