ChemicalBook Product Catalog Chemical Reagents Organic reagents Aromatic ketones 4'-HYDROXY-2'-METHYLACETOPHENONE

4'-HYDROXY-2'-METHYLACETOPHENONE

4'-HYDROXY-2'-METHYLACETOPHENONE Basic information
Product Name:4'-HYDROXY-2'-METHYLACETOPHENONE
Synonyms:4''-HYDROXY-2''-METHYLACETOPHENONE 97%;1-(4-hydroxy-2-Methylphenyl)ethan-1-one;4'-HYDROXY-2'-METHYLACETOPHENONE;4-ACETYL-3-METHYLPHENOL;2-METHYL-4-HYDROXYACETOPHENONE;Ethanone, 1-(4-hydroxy-2-methylphenyl)-;4-Hydroxy-2-Methylacetophenone 97 %;4'-Hydroxy-2'-methylacetophenone>
CAS:875-59-2
MF:C9H10O2
MW:150.17
EINECS:212-874-2
Product Categories:C9;Carbonyl Compounds;Ketones;Aromatic Acetophenones & Derivatives (substituted)
Mol File:875-59-2.mol
4'-HYDROXY-2'-METHYLACETOPHENONE Structure
4'-HYDROXY-2'-METHYLACETOPHENONE Chemical Properties
Melting point 129-131 °C(lit.)
Boiling point 313 °C(lit.)
density 1.059 g/mL at 25 °C(lit.)
refractive index 1.5369 (estimate)
storage temp. Inert atmosphere,Room Temperature
solubility soluble in Methanol
form Powder or Crystals
pka8.28±0.18(Predicted)
Specific Gravity1.059
color Off-white to beige to tan
LogP1.884 (est)
CAS DataBase Reference875-59-2(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-37/39-36
WGK Germany 3
HS Code 29145090
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
4'-HYDROXY-2'-METHYLACETOPHENONE Usage And Synthesis
Chemical Propertiesoff-white to beige crystalline powder
Uses4''-Hydroxy-2''-methylacetophenone has been used in the preparation of morpholine ketone analogs as potent histamine H3 receptor inverse agonists with wake activity.
PreparationPreparation by dealkylation of 4-hydroxy-2-methyl-5-iso-propylacetophenone with aluminium chloride in chlorobenzene at 50° (80%).
DefinitionChEBI: A member of the class of acetophenones that is acetophenone substituted by a hydroxy group at position 4 and a methyl group at position 2 respectively.
4'-HYDROXY-2'-METHYLACETOPHENONE Preparation Products And Raw materials
Preparation Products4-HYDROXY-2-METHYLBENZOIC ACID 98-->5-Hydroxy-1-indanone
1,2-DIHYDROXY-3-NITROANTHRAQUINONE 2',4'-DIHYDROXY-3'-METHYLACETOPHENONE ALLOCRYPTOPINE DISPERSE VIOLET 26 NICKEL ALIZARINATE 1,2,5,8-TETRAHYDROXYANTHRAQUINONE 2,6-DIHYDROXYANTHRAQUINONE BETA-2-ALIZARIN PRIMEVEROSIDE ANTHRACENE BROWN TIMTEC-BB SBB008992 3.4-Dimethoxy-2-hydroxy-6-methylacetophenone 5,6-Dimethoxy-1-indanone PURPUROGALLIN 5-METHOXY-1-INDANONE-3-ACETIC ACID ALIZARIN CYANIN 2-HYDROXYANTHRAQUINONE CATENARIN 7-HYDROXY-5-METHYLFLAVONE
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