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Axitinib Impurity D

Axitinib Impurity D Basic information
Product Name:Axitinib Impurity D
Synonyms:Axitinib Impurity d;Axitinib Impurity 8/(E)-N-methyl-2-(1-(2-(pyridin-2-yl)ethyl)-3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-ylthio)benzamide;N-methyl-2-[3-[(E)-2-pyridin-2-ylethenyl]-1-(2-pyridin-2-ylethyl)indazol-6-yl]sulfanylbenzamide;AxitinibG;Benzamide, N-methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1-[2-(2-pyridinyl)ethyl]-1H-indazol-6-yl]thio]-;(E)-N-Methyl-2-((1-(2-(pyridin-2-yl)ethyl)-3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)benzamide (Axitinib Impurity)
CAS:1443118-72-6
MF:C29H25N5OS
MW:491.61
EINECS:
Product Categories:
Mol File:1443118-72-6.mol
Axitinib Impurity D Structure
Axitinib Impurity D Chemical Properties
Boiling point 734.9±60.0 °C(Predicted)
density 1.23±0.1 g/cm3(Predicted)
pka14.44±0.46(Predicted)
Safety Information
MSDS Information
Axitinib Impurity D Usage And Synthesis
Uses(E)-N-methyl-2-((1-(2-(pyridin-2-yl)ethyl)-3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)benzamide is an metabolite of Axitinib(A794650) which is is a tyrosine kinase inhibitor. Axitinib is used in cancer therapy.
Axitinib Impurity D Preparation Products And Raw materials
BenzaMide, 2-[(3-iodo-1H-indazol-6-yl)thio]-N-Methyl- 2-(1H-indazol-6-ylthio)-N-Methyl- BenzaMide Axitinib Impurity 13 Axitinib Impurity 18 Axitinib Impurity 4 Axitinib Impurity 10 Axitinib Impurity 26 Axitinib Impurity a Axitinib Impurity 23 Axitinib N-Glucuronide (M7) Axitinib Impurity 3 Axitinib Impurity 14 Axitinib Impurity 19 Axitinib Impurity 11 Axitinib Impurity 28 Axitinib Impurity b Axitinib Impurity 24 Axitinib Impurity 15
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