6,7-DiMethoxy-2-(4-(tetrahydrofuran-2-carbonyl)piperazin-1-yl)quinazolin-4(1H)-one

6,7-DiMethoxy-2-(4-(tetrahydrofuran-2-carbonyl)piperazin-1-yl)quinazolin-4(1H)-one Basic information
Product Name:6,7-DiMethoxy-2-(4-(tetrahydrofuran-2-carbonyl)piperazin-1-yl)quinazolin-4(1H)-one
Synonyms:6,7-DiMethoxy-2-(4-(tetrahydrofuran-2-carbonyl)piperazin-1-yl)quinazolin-4(1H)-one;Terazosin Impurity B;Terazosin Impurity 3(Terazosin EP Impurity B);6,7-Dimethoxy-2-[4-[(tetrahydro-2-furanyl)carbonyl]-1-piperazinyl]-4(3H)-quinazolinone;Terazosin Hydrochloride Impurity Ⅲ:6,7-Dimethoxy-2-(4-(tetrahydrofuran-2-carbonyl)piperazin-1-yl)quinazolin-4(1H)-one;Terazosin EP IImpurity B;4(3H)-Quinazolinone, 6,7-dimethoxy-2-[4-[(tetrahydro-2-furanyl)carbonyl]-1-piperazinyl]-;6,7-dimethoxy-2-[4-(oxolane-2-carbonyl)piperazin-1-yl]-1H-quinazolin-4-one
CAS:1177261-73-2
MF:C19H24N4O5
MW:388.42
EINECS:
Product Categories:
Mol File:1177261-73-2.mol
6,7-DiMethoxy-2-(4-(tetrahydrofuran-2-carbonyl)piperazin-1-yl)quinazolin-4(1H)-one Structure
6,7-DiMethoxy-2-(4-(tetrahydrofuran-2-carbonyl)piperazin-1-yl)quinazolin-4(1H)-one Chemical Properties
Boiling point 615.7±65.0 °C(Predicted)
density 1.45±0.1 g/cm3(Predicted)
pka1.60±0.20(Predicted)
Safety Information
MSDS Information
6,7-DiMethoxy-2-(4-(tetrahydrofuran-2-carbonyl)piperazin-1-yl)quinazolin-4(1H)-one Usage And Synthesis
Uses6,7-Dimethoxy-2-(4-(tetrahydrofuran-2-carbonyl)piperazin-1-yl)quinazolin-4(1H)-one is an analogue of Terazosin (T105000), an α-1-adrenergicblocker related to prazosin (P702325).
6,7-DiMethoxy-2-(4-(tetrahydrofuran-2-carbonyl)piperazin-1-yl)quinazolin-4(1H)-one Preparation Products And Raw materials
Terazosin impurity 2-Piperazine-4-amino-6,7-dimethoxyquinazoline 2,2'-(1,4-Piperazinediyl)bis[6,7-diMethoxy-4-quinazolinaMine] 1-[4-(4-AMino-6,7-diMethoxy-2-quinazolinyl)-1-piperazinyl]-5-hydroxy-1-pentanone Terazosin EP IMpurity D [4-(4-AMino-7-hydroxy-6-Methoxy-2-quinazolinyl)-1-piperazinyl](tetrahydro-2-furanyl)Methanone NSC 351869 1-(2-Furoyl)piperazine [4-(4-AMino-6,7-diMethoxy-2-quinazolinyl)-1-piperazinyl][(5S)-tetrahydro-5-Methyl-2-furanyl]Methanone Terazosin hydrochloride dihydrate Piperazine, 1-[[(2R)-tetrahydro-2-furanyl]carbonyl]- (9CI) Prazosin hydrochloride Terazosin IMpurity J [4-(4-AMino-6-hydroxy-7-Methoxy-2-quinazolinyl)-1-piperazinyl](tetrahydro-2-furanyl)Methanone Terazosin EP Impurity O 1-(Tetrahydro-2-furoyl)piperazine 2-Chloro-4-amino-6,7-dimethoxyquinazoline 2-PIPERAZINE-4-AMINO-6,7-DIMETHOXY QUINOLINE HYDROCHLORIDE

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